The present investigation brought out the facts that the pupil of the cat is little affected by instillation of adrenalin, but shows, nevertheless, a greater responsiveness to adrenalin when given intravenously than does that of the rabbit, and that the duration of the dilatation effected by intravenous injection is, on the contrary, longer in the rabbit.

In regard to the vasoconstricting effect of adrenalin when administered intravenously, it was found that the intensity as well as the duration of the rise of blood pressure was greater in the rabbit than in the cat.

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