The cicatrization of sterile wounds may be studied in the same way as an ordinary physicochemical phenomenon. It is possible, therefore, to express the law of cicatrization by a mathematical equation as soon as an accurate measure of the wound can be obtained. By means of the equation, a curve is obtained which represents the theoretical evolution of the cicatrization of a wound. This curve, being an expression of what should happen on a normal wound, healing aseptically, on a normal man, is a daily point of comparison to what appears actually on the observed wound, and allows one to study accurately the fluctuations of cicatrization on a given individual, and the action of different dressings and antiseptic substances
Article| November 01 1916
CICATRIZATION OF WOUNDS : II. MATHEMATICAL EXPRESSION OF THE CURVE REPRESENTING CICATRIZATION.
P. Lecomte Du Noüy
From the Laboratories of The Rockefeller Institute for Medical Research, New York, and Hospital 21, Compiègne, France.
Received: May 24 1916
Online Issn: 1540-9538
Print Issn: 0022-1007
Copyright, 1916, by The Rockefeller Institute for Medical Research New York
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P. Lecomte Du Noüy; CICATRIZATION OF WOUNDS : II. MATHEMATICAL EXPRESSION OF THE CURVE REPRESENTING CICATRIZATION. . J Exp Med 1 November 1916; 24 (5): 451–460. doi: https://doi.org/10.1084/jem.24.5.451
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