1. Liver tissue showing fatty degeneration obtained from animals poisoned with phosphorus or chloroform contains a decreased amount of esterase.

2. The serum of animals poisoned with phosphorus or chloroform has a high esterase activity.

3. The increased amount of esterase in the serum is not derived from the disintegrating liver cells as the esterase in the blood of the hepatic vein is less than that found elsewhere.

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