Previous studies have indicated that LLA-DR homozygous cell lines express two DR molecules but only a single DS (I-A-like) molecule. This report demonstrates that an HLA-DR5 homozygous cell line expresses at least two distinct DS molecules. These two DS molecules are formed by the association of a single DS alpha chain with either of two DS beta chains. Four distinct Ia molecules have now been identified from this DR5 homozygous cell line.
An HLA-DR5 homozygous cell line expresses two DS (I-A-like) molecules.
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R W Karr, C C Kannapell, R J Zangara, S M Goyert, J Silver, B D Schwartz; An HLA-DR5 homozygous cell line expresses two DS (I-A-like) molecules.. J Exp Med 1 October 1983; 158 (4): 1374–1379. doi: https://doi.org/10.1084/jem.158.4.1374
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