The presence of H-2 antigens of the paternal and maternal haplotypes on mouse trophoblast cells was examined at several stages of pregnancy by using a sensitive immunolabeling technique followed by quantitative radioautography. Results revealed the presence of H-2 antigens (determined by the K or D loci) of both parental haplotypes on the F1 trophoblast cells. At 14-16 d of gestation, the antigen density was equivalent to that on adult thymocytes and there was a further 50% increase on day 18. H-2 antigens of both parental haplotypes are also found to be expressed on 11-13 d trophoblast cells.
Article| May 01 1979
Localization of H-2 antigens on mouse trophoblast cells.
P K Lala
Online Issn: 1540-9538
Print Issn: 0022-1007
J Exp Med (1979) 149 (5): 1238–1253.
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S Chatterjee-Hasrouni, P K Lala; Localization of H-2 antigens on mouse trophoblast cells.. J Exp Med 1 May 1979; 149 (5): 1238–1253. doi: https://doi.org/10.1084/jem.149.5.1238
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