CBH to DNP-GL could be elicited only in responder guinea pigs which possess the genetic ability to develop classic delayed type hypersensitivity to DNP-PLL, the response to which is governed by the same gene. Since the defect in nonresponder animals seems to reside at the level of their T cells and not B cells, these results lend support to the contention that CBH, as well as DH, is dependent on and probably mediated by T cells.
Article| January 01 1976
Genetic control of cutaneous basophil hypersensitivity.
Online Issn: 1540-9538
Print Issn: 0022-1007
J Exp Med (1976) 143 (1): 206–210.
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M Stadecker, S Leskowitz; Genetic control of cutaneous basophil hypersensitivity.. J Exp Med 1 January 1976; 143 (1): 206–210. doi: https://doi.org/10.1084/jem.143.1.206
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