Lymphocytes, from randomly selected individuals having normal immune function, when incubated in vitro with varying concentrations of streptococcal antigens, responded in three ways: (a) response over the entire antigen concentration range, i.e., responders; (b) low response to only the highest antigen concentrations; and (c) no response at any antigen concentration. Frequency distribution analysis of these groups indicated that a significant association occurred between the ability to respond and HL-A 5.
Article| May 01 1975
Association of HL-A 5 and immune responsiveness in vitro to streptococcal antigens.
L J Greenberg
E D Gray
E J Yunis
Online ISSN: 1540-9538
Print ISSN: 0022-1007
J Exp Med (1975) 141 (5): 935–943.
L J Greenberg, E D Gray, E J Yunis; Association of HL-A 5 and immune responsiveness in vitro to streptococcal antigens.. J Exp Med 1 May 1975; 141 (5): 935–943. doi: https://doi.org/10.1084/jem.141.5.935
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