Specific alloantibody admixed with a grafted murine lymphoma is suppressive of the graft in mice of the inbred strain native to the tumor. Suppressive capacity of the host is obviated in mice given 500 R whole body irradiation before tumor inoculation but is restored when normal peritoneal macrophages are admixed with the tumor-antibody inoculum. Other normal cell types admixed with the tumor-antibody inoculum are not effective in restoring suppressive capacity.
ANTIBODY-MEDIATED SUPPRESSION OF GRAFTED LYMPHOMA CELLS : II. PARTICIPATION OF MACROPHAGES
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Hyun S. Shin, Nathan Kaliss, David Borenstein, Maurice K. Gately; ANTIBODY-MEDIATED SUPPRESSION OF GRAFTED LYMPHOMA CELLS : II. PARTICIPATION OF MACROPHAGES . J Exp Med 1 August 1972; 136 (2): 375–380. doi: https://doi.org/10.1084/jem.136.2.375
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