Skip to Main Content
Skip Nav Destination
Article navigation
Volume 131, Issue 3
1 March 1970
Journal of Experimental Medicine Cover Image for Volume 131, Issue 3
Article| March 01 1970

ASSOCIATION OF LACTOFERRIN WITH SPECIFIC GRANULES IN RABBIT HETEROPHIL LEUKOCYTES

M. Baggiolini,
M. Baggiolini
From The Rockefeller University, New York 10021, and the Department of Experimental Medicine, Cliniques Universitaires Saint-Pierre, Université de Louvain, Belgium
Search for other works by this author on:
This Site
PubMed
Google Scholar
C. de Duve,
C. de Duve
From The Rockefeller University, New York 10021, and the Department of Experimental Medicine, Cliniques Universitaires Saint-Pierre, Université de Louvain, Belgium
Search for other works by this author on:
This Site
PubMed
Google Scholar
P. L. Masson,
P. L. Masson
From The Rockefeller University, New York 10021, and the Department of Experimental Medicine, Cliniques Universitaires Saint-Pierre, Université de Louvain, Belgium
Search for other works by this author on:
This Site
PubMed
Google Scholar
J. F. Heremans
J. F. Heremans
From The Rockefeller University, New York 10021, and the Department of Experimental Medicine, Cliniques Universitaires Saint-Pierre, Université de Louvain, Belgium
Search for other works by this author on:
This Site
PubMed
Google Scholar
Crossmark: Check for Updates
Author and Article Information
M. Baggiolini
From The Rockefeller University, New York 10021, and the Department of Experimental Medicine, Cliniques Universitaires Saint-Pierre, Université de Louvain, Belgium
C. de Duve
From The Rockefeller University, New York 10021, and the Department of Experimental Medicine, Cliniques Universitaires Saint-Pierre, Université de Louvain, Belgium
P. L. Masson
From The Rockefeller University, New York 10021, and the Department of Experimental Medicine, Cliniques Universitaires Saint-Pierre, Université de Louvain, Belgium
J. F. Heremans
From The Rockefeller University, New York 10021, and the Department of Experimental Medicine, Cliniques Universitaires Saint-Pierre, Université de Louvain, Belgium
Received: October 20 1969
Online ISSN: 1540-9538
Print ISSN: 0022-1007
Copyright © 1970 by The Rockefeller University Press
1970
J Exp Med (1970) 131 (3): 559–570.
https://doi.org/10.1084/jem.131.3.559
Article history
Received:
October 20 1969

Lactoferrin has been identified in rabbit heterophil leukocytes on the basis of its immunological reactivity, electrophoretic mobility, acid-resistant iron-binding properties, and spectral characteristics.

Leukocyte lactoferrin was found to be exclusively localized in the specific (secondary) granules, which have been resolved from other subcellular components by zonal differential centrifugation and by isopycnic equilibration.

This content is only available as a PDF.
Copyright © 1970 by The Rockefeller University Press
1970
You do not currently have access to this content.
Don't already have an account? Register
699 Views
187 Crossref
View Metrics

Suggested Content

THE INVOLVEMENT OF LACTOFERRIN IN THE HYPOSIDEREMIA OF ACUTE INFLAMMATION
LACTOFERRIN, AN IRON-BINBING PROTEIN NI NEUTROPHILIC LEUKOCYTES
Multiple molecular forms of human lactoferrin. Identification of a class of lactoferrins that possess ribonuclease activity and lack iron-binding capacity.

Advertisement

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal