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Volume 116, Issue 5
1 November 1962
Journal of Experimental Medicine Cover Image for Volume 116, Issue 5
Article| November 01 1962

THE EFFECT OF 6-MERCAPTOPURINE ON DELAYED HYPERSENSITIVITY IN GUINEA PIGS

John R. Hoyer,
John R. Hoyer
From the Pediatric Research Laboratories of the Variety Club Heart Hospital, University of Minnesota, Minneapolis
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Leon W. Hoyer,
Leon W. Hoyer
From the Pediatric Research Laboratories of the Variety Club Heart Hospital, University of Minnesota, Minneapolis
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Robert A. Good,
Robert A. Good
From the Pediatric Research Laboratories of the Variety Club Heart Hospital, University of Minnesota, Minneapolis
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Richard M. Condie
Richard M. Condie
From the Pediatric Research Laboratories of the Variety Club Heart Hospital, University of Minnesota, Minneapolis
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Author and Article Information
John R. Hoyer
From the Pediatric Research Laboratories of the Variety Club Heart Hospital, University of Minnesota, Minneapolis
Leon W. Hoyer
From the Pediatric Research Laboratories of the Variety Club Heart Hospital, University of Minnesota, Minneapolis
Robert A. Good
From the Pediatric Research Laboratories of the Variety Club Heart Hospital, University of Minnesota, Minneapolis
Richard M. Condie
From the Pediatric Research Laboratories of the Variety Club Heart Hospital, University of Minnesota, Minneapolis
Received: June 22 1962
Online ISSN: 1540-9538
Print ISSN: 0022-1007
©Copyright, 1962, by The Rockefeller Institute
1962
J Exp Med (1962) 116 (5): 679–685.
https://doi.org/10.1084/jem.116.5.679
Article history
Received:
June 22 1962

The development of tuberculin hypersensitivity in guinea pigs after BCG stimulation was suppressed by intramuscular administration of 50 mg/kg/day of 6-mercaptopurine started at the time of stimulation. Fasting of guinea pigs after BCG stimulation had no effect on the development of tuberculin hypersensitivity.

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©Copyright, 1962, by The Rockefeller Institute
1962
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