1. After thyroidectomy the glycosuria, produced by ether or adrenalin in the normal animal, is greatly reduced.

2. Thyroidless dogs fed on powdered thyroid glands show a return of glycosuria more or less proportional to the amount ingested when treated with adrenalin or ether.

3. As the thyroids regenerate the ether or adrenalin glycosuria increases similarly.

The results of these experiments leave no doubt in our minds that the secretion of the thyroid glands is connected in some obscure way with the metabolism of sugar in the body or exerts some control over organs whose duty it is to participate in the sugar metabolism.

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