A final concentration of 3 x 10–5 M spermine or spermidine inhibited the growth of mammalian tubercle bacilli in a modified Dubos liquid medium. Various related amino compounds, including isolated portions of the spermine molecule and the products of its chemical degradation, did not manifest similar antimycobacterial activity.
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Copyright, 1953, by The Rockefeller Institute for Medical Research New York
1953
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