The external symptoms of suprarenal insufficiency in cats with diabetes insipidus are the same as in those animals with only the suprarenals removed, except that the symptoms develop more rapidly in the former. The serum electrolyte changes, however, are different; there is no consistent or marked decrease in the concentration of sodium or chloride following suprarenalectomy in cats with diabetes insipidus, but there is the usual increase in the concentration of potassium. It is suggested that this indicates that changes in sodium are less characteristic of suprarenal insufficiency than are disturbances of potassium metabolism or distribution. A possible inter-relationship between the suprarenal cortex and the posterior lobe of the pituitary as salt-regulating mechanisms is discussed.
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1 February 1938
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February 01 1938
SERUM SODIUM, POTASSIUM AND CHLORIDE AFTER SUPRARENALECTOMY IN CATS WITH DIABETES INSIPIDUS
Charles A. Winter,
Charles A. Winter
From the Departments of Physiology, Pharmacology and Anatomy, State University of Iowa, Iowa City
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E. G. Gross,
E. G. Gross
From the Departments of Physiology, Pharmacology and Anatomy, State University of Iowa, Iowa City
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W. R. Ingram
W. R. Ingram
From the Departments of Physiology, Pharmacology and Anatomy, State University of Iowa, Iowa City
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Charles A. Winter
From the Departments of Physiology, Pharmacology and Anatomy, State University of Iowa, Iowa City
E. G. Gross
From the Departments of Physiology, Pharmacology and Anatomy, State University of Iowa, Iowa City
W. R. Ingram
From the Departments of Physiology, Pharmacology and Anatomy, State University of Iowa, Iowa City
Received:
October 17 1937
Online ISSN: 1540-9538
Print ISSN: 0022-1007
Copyright, 1938, by The Rockefeller Institute for Medical Research New York
1938
J Exp Med (1938) 67 (2): 251–265.
Article history
Received:
October 17 1937
Citation
Charles A. Winter, E. G. Gross, W. R. Ingram; SERUM SODIUM, POTASSIUM AND CHLORIDE AFTER SUPRARENALECTOMY IN CATS WITH DIABETES INSIPIDUS . J Exp Med 1 February 1938; 67 (2): 251–265. doi: https://doi.org/10.1084/jem.67.2.251
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