ACTIVE IMMUNIZATION AGAINST POLIOMYELITIS

Brodie , Maurice

doi:10.1084/jem.56.4.493

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Article| October 01 1932

ACTIVE IMMUNIZATION AGAINST POLIOMYELITIS

Maurice Brodie

From the Department of Bacteriology, McGill University, Montreal, Canada

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Author and Article Information

Maurice Brodie

From the Department of Bacteriology, McGill University, Montreal, Canada

Received: June 22 1932

Online ISSN: 1540-9538

Print ISSN: 0022-1007

Copyright, 1932, by The Rockefeller Institute for Medical Research New York

1932

J Exp Med (1932) 56 (4): 493–505.

https://doi.org/10.1084/jem.56.4.493

1. A single intracutaneous inoculation with a subinfective dose of the virus of poliomyelitis produces considerable immunity.

2. Virus-serum combinations produce an appreciable immunity, providing just sufficient serum is used to protect the animal from paralysis. If there is an excess of serum, the degree of immunity is considerably reduced.

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Copyright, 1932, by The Rockefeller Institute for Medical Research New York

1932

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