SPOTTED FEVER I. INTRANUCLEAR RICKETTSIAE IN SPOTTED FEVER STUDIED IN TISSUE CULTURE

Pinkerton , Henry; Hass , G. M.

doi:10.1084/jem.56.1.151

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Article| July 01 1932

SPOTTED FEVER : I. INTRANUCLEAR RICKETTSIAE IN SPOTTED FEVER STUDIED IN TISSUE CULTURE

Henry Pinkerton,

Henry Pinkerton

From the Department of Pathology, Harvard Medical School, Boston

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G. M. Hass

From the Department of Pathology, Harvard Medical School, Boston

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Author and Article Information

Henry Pinkerton

From the Department of Pathology, Harvard Medical School, Boston

G. M. Hass

From the Department of Pathology, Harvard Medical School, Boston

Received: March 28 1932

Online ISSN: 1540-9538

Print ISSN: 0022-1007

Copyright, 1932, by The Rockefeller Institute for Medical Research New York

1932

J Exp Med (1932) 56 (1): 151–156.

https://doi.org/10.1084/jem.56.1.151

Spotted fever infection has been studied in tissue cultures grown at 32°C. The behavior of spotted fever Rickettsiaeis compared and contrasted with that of typhus Rickettsiae under similar conditions. The spotted fever organisms multiply extensively in the nuclei of cells where they form spherical clusters of various sizes. These structures are compared and contrasted with intranuclear inclusion bodies.

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Copyright, 1932, by The Rockefeller Institute for Medical Research New York

1932

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