1. A quantitative study of the reaction between the soluble specific substance of Type III pneumococcus and its homologous antibody has been made.

2. The entire reaction, from excess of antibody, to excess of specific substance with its accompanying inhibition zone effect, may be expressed by three mass-law equations.

3. The significance of these findings is discussed.

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Copyright, 1929, by The Rockefeller Institute for Medical Research New York
1929
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