The onset of spontaneous snuffles in rabbits at The Rockefeller Institute is preceded by the appearance in the nasal passages of Bacterium lepisepticum.

The active stages of snuffles infection are associated with the presence in these passages of large numbers of this bacterium.

Spontaneous recovery from snuffles is associated with a diminution in number or a disappearance of these bacteria from the nasal passages.

Various experimental procedures reduce the resistance of rabbits to spontaneous snuffles.

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Copyright, 1924, by The Rockefeller Institute for Medical Research New York
1924
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