1. The resistance of rats to bacterial intoxication is greatly decreased after double adrenalectomy.
2. This decreased resistance is dependent upon a functional insufficiency of the adrenal cortex.
3. A dose of killed streptococci or staphylococci can be obtained that is invariably fatal to adrenalectomized rats, before hypertrophy of cortical accessories, but never kills control rats.
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Copyright, 1924, by The Rockefeller Institute for Medical Research New York
1924
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