Studies with polio-infected HeLa cells using cell disruption techniques during the early stages of infection have shown that:
The inoculum of poliovirus adsorbed on HeLa cells is largely inactivated. Infective virus accumulates in a monolayer sheet of cells in advance of release into the medium.
The eclipse period is shorter in multiply infected cells than in those infected with a single particle.
This content is only available as a PDF.
Copyright, 1958, by The Rockefeller Institute for Medical Research New York
1958
You do not currently have access to this content.
