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Virginia M-Y. Lee
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Journal Articles

α-Synuclein modulates tau spreading in mouse brains

In Special Collection:
Neurodegenerative Diseases: Biology & Therapeutics , Neurodegenerative Diseases: Emerging Mechanisms and Therapeutic Opportunities
Fares Bassil, Emily S. Meymand, Hannah J. Brown, Hong Xu, Timothy O. Cox, Shankar Pattabhiraman, Chantal M. Maghames, Qihui Wu, Bin Zhang, John Q. Trojanowski, Virginia M.-Y. Lee
Journal: Journal of Experimental Medicine
J Exp Med (2020) 218 (1): e20192193.
https://doi.org/10.1084/jem.20192193
Published: 22 October 2020
View article titled, α-Synuclein modulates tau spreading in mouse brains
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Includes: Supplementary data
Journal Articles

Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease

Nolwen L. Rey, Jennifer A. Steiner, Nazia Maroof, Kelvin C. Luk, Zachary Madaj, John Q. Trojanowski, Virginia M.-Y. Lee, Patrik Brundin
Journal: Journal of Experimental Medicine
J Exp Med (2016) 213 (9): 1759–1778.
https://doi.org/10.1084/jem.20160368
Published: 08 August 2016
View article titled, Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease
Open the PDF for Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease in another window
Includes: Supplementary data
Journal Articles

BACE overexpression alters the subcellular processing of APP and inhibits Aβ deposition in vivo

Edward B. Lee, Bin Zhang, Kangning Liu, Eric A. Greenbaum, Robert W. Doms, John Q. Trojanowski, Virginia M.-Y. Lee
Journal: Journal of Cell Biology
J Cell Biol (2005) 168 (2): 291–302.
https://doi.org/10.1083/jcb.200407070
Published: 10 January 2005
View article titled, BACE overexpression alters the subcellular processing of APP and inhibits Aβ deposition in vivo
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Includes: Supplementary data
Journal Articles

Degradative organelles containing mislocalized α- and β-synuclein proliferate in presenilin-1 null neurons

Christina A. Wilson, Diane D. Murphy, Benoit I. Giasson, Bin Zhang, John Q. Trojanowski, Virginia M.-Y. Lee
Journal: Journal of Cell Biology
J Cell Biol (2004) 165 (3): 335–346.
https://doi.org/10.1083/jcb.200403061
Published: 03 May 2004
View article titled, Degradative organelles containing mislocalized α- and β-synuclein proliferate in presenilin-1 null neurons
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Journal Articles

Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density

Mala V. Rao, Linda J. Engle, Panaiyur S. Mohan, Aidong Yuan, Dike Qiu, Anne Cataldo, Linda Hassinger, Stephen Jacobsen, Virginia M-Y. Lee, Athena Andreadis, Jean-Pierre Julien, Paul C. Bridgman, Ralph A. Nixon
Journal: Journal of Cell Biology
J Cell Biol (2002) 159 (2): 279–290.
https://doi.org/10.1083/jcb.200205062
Published: 28 October 2002
View article titled, Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density
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Journal Articles

Requirement of Heavy Neurofilament Subunit in the Development of Axons with Large Calibers

Gregory A. Elder, Victor L. Friedrich, Jr., Chulho Kang, Paolo Bosco, Andrei Gourov, Pang-Hsien Tu, Bin Zhang, Virginia M.-Y. Lee, Robert A. Lazzarini
Journal: Journal of Cell Biology
J Cell Biol (1998) 143 (1): 195–205.
https://doi.org/10.1083/jcb.143.1.195
Published: 05 October 1998
View article titled, Requirement of Heavy Neurofilament Subunit in the Development of Axons with Large Calibers
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Journal Articles

Detection of a Novel Intraneuronal Pool of Insoluble Amyloid β Protein that Accumulates with Time in Culture

Daniel M. Skovronsky, Robert W. Doms, Virginia M.-Y. Lee
Journal: Journal of Cell Biology
J Cell Biol (1998) 141 (4): 1031–1039.
https://doi.org/10.1083/jcb.141.4.1031
Published: 18 May 1998
View article titled, Detection of a Novel Intraneuronal Pool of Insoluble Amyloid β Protein that Accumulates with Time in Culture
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Journal Articles

Absence of the Mid-sized Neurofilament Subunit Decreases Axonal Calibers, Levels of Light Neurofilament (NF-L), and Neurofilament Content

Gregory A. Elder, Victor L. Friedrich, Jr., Paolo Bosco, Chulho Kang, Andrei Gourov, Pang-Hsien Tu, Virginia M.-Y. Lee, Robert A. Lazzarini
Journal: Journal of Cell Biology
J Cell Biol (1998) 141 (3): 727–739.
https://doi.org/10.1083/jcb.141.3.727
Published: 04 May 1998
View article titled, Absence of the Mid-sized Neurofilament Subunit Decreases Axonal Calibers, Levels of Light Neurofilament (NF-L), and Neurofilament Content
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Journal Articles

Neurofilaments and Orthograde Transport Are Reduced in Ventral Root Axons of Transgenic Mice that Express Human SOD1 with a G93A Mutation

Bin Zhang, Pang-hsien Tu, Farhad Abtahian, John Q. Trojanowski, Virginia M.-Y. Lee
Journal: Journal of Cell Biology
J Cell Biol (1997) 139 (5): 1307–1315.
https://doi.org/10.1083/jcb.139.5.1307
Published: 01 December 1997
View article titled, Neurofilaments and Orthograde Transport Are Reduced in Ventral Root Axons of Transgenic Mice that Express Human SOD1 with a G93A Mutation
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Journal Articles

Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells

Abraham S.C. Chyung, Barry D. Greenberg, David G. Cook, Robert W. Doms, Virginia M.-Y. Lee
Journal: Journal of Cell Biology
J Cell Biol (1997) 138 (3): 671–680.
https://doi.org/10.1083/jcb.138.3.671
Published: 11 August 1997
View article titled, Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells
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