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Stuart Tangye
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Journal Articles

Repair or Despair? Balancing Conditioning Risks in Stem Cell Transplant for LIGASE 1-Deficient Severe Combined Immunodeficiency

Tiarni Templeton, Mounavi Vemula, Lisa Woodbine, Marcus Hinchcliffe, Stuart Tangye, Christopher Fraser, Anna Sullivan, Alberto Pinzon-Charry
Journal: Journal of Human Immunity
Series: ASCIA CGR/IEI Conference Abstracts 2025
J Hum Immun (2025) 1 (ASCIA2025): eASCIA2025abstract.cgr18.
https://doi.org/10.70962/ASCIA2025abstract.cgr18
Published: 26 November 2025
View article titled, Repair or Despair? Balancing Conditioning Risks in Stem Cell Transplant for LIGASE 1-Deficient Severe Combined Immunodeficiency
Journal Articles

Overactive STAT3 Dysregulates BCR Signalling and Drives Accumulation and Autoreactivity of Disease-Associated CD21low B Cells

Etienne Masle-Farquhar, Timothy Peters, Katherine Jackson, Blake Bowen, Danielle Avery, Erica Schmitt, Christopher Jara, Ania Moxon, Joseph Mackie, Megan L. Faulks, Mandeep Singh, Anna Forster, Daniel Suan, Gulbu Uzel, Hassan Abolhassani, Ignatius Chua, Jennifer W Leiding, Kaarina Heiskanen, Kahn Preece, Leena Kainulainen, Michael O’Sullivan, Mikko Seppänen, Satu Mustjoki, Shannon Brothers, Tiphanie Vogel, Megan Cooper, Owen Siggs, Cindy Ma, Peter McNaughton, Robert Brink, Joseph Powell, Stuart Tangye, Joanne Reed, Christopher Goodnow
Journal: Journal of Human Immunity
Series: ASCIA CGR/IEI Conference Abstracts 2025
J Hum Immun (2025) 1 (ASCIA2025): eASCIA2025abstract.p162.
https://doi.org/10.70962/ASCIA2025abstract.p162
Published: 26 November 2025
View article titled, Overactive STAT3 Dysregulates BCR Signalling and Drives Accumulation and Autoreactivity of Disease-Associated CD21low B Cells
Journal Articles

Enhancer Hijacking of the IGH Locus as a Novel Genetic Mechanism of an Inborn Error of Immunity Leading to Invasive Streptococcus pneumoniae Infection due to Antibody Deficiency

Joshua Tobin, Matthew Du, Changxu Fan, Tony Yao, Birk Evavold, Alexander Paul, Ana Kolicheski, Yongjun Wang, Nermina Saucier, Jennifer Poursine-Laurent, Kristen McDaniels, Rachel Bielecki, Tomoki Kawai, Peggy Kendall, Caroline Horner, Naresha Saligrama, David LaFon, John Kuster, Luigi Notarangelo, Richard James, Stuart Tangye, Ting Wang, Jeffrey Bednarski, Neil Romberg, Ali Ellebedy, Megan Cooper
Journal: Journal of Human Immunity
Series: CIS Meeting Abstracts 2025
J Hum Immun (2025) 1 (CIS2025): CIS2025abstract.119.
https://doi.org/10.70962/CIS2025abstract.119
Published: 25 April 2025
View article titled, Enhancer Hijacking of the IGH Locus as a Novel Genetic Mechanism of an Inborn Error of Immunity Leading to Invasive Streptococcus pneumoniae Infection due to Antibody Deficiency
Journal Articles

Impaired Development of Memory B Cells and Antibody Responses in Humans Deficient in PD-1 Signaling

Stuart Tangye
Journal: Journal of Human Immunity
Series: CIS Meeting Abstracts 2025
J Hum Immun (2025) 1 (CIS2025): CIS2025abstract.214.
https://doi.org/10.70962/CIS2025abstract.214
Published: 25 April 2025
View article titled, Impaired Development of Memory B Cells and Antibody Responses in Humans Deficient in PD-1 Signaling
Journal Articles

Unravelling Enigmatic IgE-Expressing B Cells by Studying Patients with Monogenic Atopic Disorders

Stuart Tangye, Karrnan Pathmanandavel, Will Figgett, Leonard Goldstein, Paul Gray, Melanie Wong, Cindy Ma
Journal: Journal of Human Immunity
Series: CIS Meeting Abstracts 2025
J Hum Immun (2025) 1 (CIS2025): CIS2025abstract.102.
https://doi.org/10.70962/CIS2025abstract.102
Published: 25 April 2025
View article titled, Unravelling Enigmatic IgE-Expressing B Cells by Studying Patients with Monogenic Atopic Disorders