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Megan Cooper
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Journal Articles

Overactive STAT3 Dysregulates BCR Signalling and Drives Accumulation and Autoreactivity of Disease-Associated CD21low B Cells

Etienne Masle-Farquhar, Timothy Peters, Katherine Jackson, Blake Bowen, Danielle Avery, Erica Schmitt, Christopher Jara, Ania Moxon, Joseph Mackie, Megan L. Faulks, Mandeep Singh, Anna Forster, Daniel Suan, Gulbu Uzel, Hassan Abolhassani, Ignatius Chua, Jennifer W Leiding, Kaarina Heiskanen, Kahn Preece, Leena Kainulainen, Michael O’Sullivan, Mikko Seppänen, Satu Mustjoki, Shannon Brothers, Tiphanie Vogel, Megan Cooper, Owen Siggs, Cindy Ma, Peter McNaughton, Robert Brink, Joseph Powell, Stuart Tangye, Joanne Reed, Christopher Goodnow
Journal: Journal of Human Immunity
Series: ASCIA CGR/IEI Conference Abstracts 2025
J Hum Immun (2025) 1 (ASCIA2025): eASCIA2025abstract.p162.
https://doi.org/10.70962/ASCIA2025abstract.p162
Published: 26 November 2025
View article titled, Overactive STAT3 Dysregulates BCR Signalling and Drives Accumulation and Autoreactivity of Disease-Associated CD21low B Cells
Journal Articles

Enhancer Hijacking of the IGH Locus as a Novel Genetic Mechanism of an Inborn Error of Immunity Leading to Invasive Streptococcus pneumoniae Infection due to Antibody Deficiency

Joshua Tobin, Matthew Du, Changxu Fan, Tony Yao, Birk Evavold, Alexander Paul, Ana Kolicheski, Yongjun Wang, Nermina Saucier, Jennifer Poursine-Laurent, Kristen McDaniels, Rachel Bielecki, Tomoki Kawai, Peggy Kendall, Caroline Horner, Naresha Saligrama, David LaFon, John Kuster, Luigi Notarangelo, Richard James, Stuart Tangye, Ting Wang, Jeffrey Bednarski, Neil Romberg, Ali Ellebedy, Megan Cooper
Journal: Journal of Human Immunity
Series: CIS Meeting Abstracts 2025
J Hum Immun (2025) 1 (CIS2025): CIS2025abstract.119.
https://doi.org/10.70962/CIS2025abstract.119
Published: 25 April 2025
View article titled, Enhancer Hijacking of the IGH Locus as a Novel Genetic Mechanism of an Inborn Error of Immunity Leading to Invasive Streptococcus pneumoniae Infection due to Antibody Deficiency
Journal Articles

Deep Sequencing Reveals Somatic Mosaicism in Genes Relevant to Genetic Errors of Immunity in a Cohort of Patients with Immune Dysregulation

Elizabeth Schmitz, Alexander Paul, Rajarshi Ghosh, Nermina Saucier, Ana Kolicheski, Sammy Risma, Tiphanie Vogel, Eric Allenspach, David Hoytema van Konijnenburg, Craig Platt, Megan Elkins, Jolan Walter, Katie Lewis, Adriana de Jesus, Raphaela Goldbach-Mansky, Jessica Durkee-Shock, Jeffrey Cohen, Irini Sereti, Andrea Lisco, Ottavia Delmonte, Luigi Notarangelo, V. Rao, Morgan Similuk, Steven Holland, Malachi Griffith, Obi Griffith, Magdalena Walkiewicz, Megan Cooper
Journal: Journal of Human Immunity
Series: CIS Meeting Abstracts 2025
J Hum Immun (2025) 1 (CIS2025): CIS2025abstract.120.
https://doi.org/10.70962/CIS2025abstract.120
Published: 25 April 2025
View article titled, Deep Sequencing Reveals Somatic Mosaicism in Genes Relevant to Genetic Errors of Immunity in a Cohort of Patients with Immune Dysregulation
Journal Articles

Autologous Lentiviral Vector LVFOXP3 CD4 T Cells for IPEX Syndrome

Jessie Alexander, Rajni Agarwal, Alaa Alkayed, Akshaya Ramachandran, Katherine Joseph, Julia Ye, Bing Wang, Simon Borna, Yu-Hsuan Kuo, Prachi Wani, Fariba Fazeli, Kunjan Kamdar, Niranchana Vallirajan, Kirstin Dougall, Erica Goodwin, Gopin Saini, Megan Cooper, Isabelle Meyts, Giorgia Bucciol, Leonardo Oliveira Mendonca, Hey Chong, Clinton Dunn, Maria Grazia Roncorolo, Rosa Bacchetta
Journal: Journal of Human Immunity
Series: CIS Meeting Abstracts 2025
J Hum Immun (2025) 1 (CIS2025): CIS2025abstract.27.
https://doi.org/10.70962/CIS2025abstract.27
Published: 25 April 2025
View article titled, Autologous Lentiviral Vector LVFOXP3 CD4 T Cells for IPEX Syndrome