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Michael O’Sullivan
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Journal Articles

Overactive STAT3 Dysregulates BCR Signalling and Drives Accumulation and Autoreactivity of Disease-Associated CD21low B Cells

Etienne Masle-Farquhar, Timothy Peters, Katherine Jackson, Blake Bowen, Danielle Avery, Erica Schmitt, Christopher Jara, Ania Moxon, Joseph Mackie, Megan L. Faulks, Mandeep Singh, Anna Forster, Daniel Suan, Gulbu Uzel, Hassan Abolhassani, Ignatius Chua, Jennifer W Leiding, Kaarina Heiskanen, Kahn Preece, Leena Kainulainen, Michael O’Sullivan, Mikko Seppänen, Satu Mustjoki, Shannon Brothers, Tiphanie Vogel, Megan Cooper, Owen Siggs, Cindy Ma, Peter McNaughton, Robert Brink, Joseph Powell, Stuart Tangye, Joanne Reed, Christopher Goodnow
Journal: Journal of Human Immunity
Series: ASCIA CGR/IEI Conference Abstracts 2025
J Hum Immun (2025) 1 (ASCIA2025): eASCIA2025abstract.p162.
https://doi.org/10.70962/ASCIA2025abstract.p162
Published: 26 November 2025
View article titled, Overactive STAT3 Dysregulates BCR Signalling and Drives Accumulation and Autoreactivity of Disease-Associated CD21low B Cells
Journal Articles

Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production

Anthony Lau, Danielle T. Avery, Katherine Jackson, Helen Lenthall, Stefano Volpi, Henry Brigden, Amanda J. Russell, Julia Bier, Joanne H. Reed, Joanne M. Smart, Theresa Cole, Sharon Choo, Paul E. Gray, Lucinda J. Berglund, Peter Hsu, Melanie Wong, Michael O’Sullivan, Kaan Boztug, Isabelle Meyts, Gulbu Uzel, Luigi D. Notarangelo, Robert Brink, Christopher C. Goodnow, Stuart G. Tangye, Elissa K. Deenick
Journal: Journal of Experimental Medicine
J Exp Med (2019) 217 (2): e20191336.
https://doi.org/10.1084/jem.20191336
Published: 16 December 2019
View article titled, Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production
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Includes: Supplementary data
Journal Articles

Germline-activating mutations in PIK3CD compromise B cell development and function

In Special Collection:
Inborn Errors of Immunity 2019
Danielle T. Avery, Alisa Kane, Tina Nguyen, Anthony Lau, Akira Nguyen, Helen Lenthall, Kathryn Payne, Wei Shi, Henry Brigden, Elise French, Julia Bier, Jana R. Hermes, David Zahra, William A. Sewell, Danyal Butt, Michael Elliott, Kaan Boztug, Isabelle Meyts, Sharon Choo, Peter Hsu, Melanie Wong, Lucinda J. Berglund, Paul Gray, Michael O’Sullivan, Theresa Cole, Steven M. Holland, Cindy S. Ma, Christoph Burkhart, Lynn M. Corcoran, Tri Giang Phan, Robert Brink, Gulbu Uzel, Elissa K. Deenick, Stuart G. Tangye
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (8): 2073–2095.
https://doi.org/10.1084/jem.20180010
Published: 17 July 2018
View article titled, Germline-activating mutations in PIK3CD compromise B cell development and function
Open the PDF for Germline-activating mutations in PIK3CD compromise B cell development and function in another window
Includes: Supplementary data