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Journal Articles

Moesin controls cell–cell fusion and osteoclast function

Ophélie Dufrançais, Marianna Plozza, Marie Juzans, Arnaud Métais, Sarah C. Monard, Pierre-Jean Bordignon, Perrine Verdys, Thibaut Sanchez, Martin Bergert, Julia Halper, Christopher J. Panebianco, Rémi Mascarau, Rémi Gence, Gaëlle Arnaud, Myriam Ben Neji, Isabelle Maridonneau-Parini, Véronique Le Cabec, Joel D. Boerckel, Nathan J. Pavlos, Alba Diz-Muñoz, Frédéric Lagarrigue, Claudine Blin-Wakkach, Sébastien Carréno, Renaud Poincloux, Janis K. Burkhardt, Brigitte Raynaud-Messina, Christel Vérollet
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (11): e202409169.
https://doi.org/10.1083/jcb.202409169
Published: 27 October 2025
View article titled, Moesin controls cell–cell fusion and osteoclast function
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Includes: Supplementary data
Journal Articles

Dissecting the HLH Immune Synapse: Critical Roles for Termination, Cytokine Intensity, and Target Cell Death

Anastasia Frank-Kamenetskii, Hannah Klinghoffer, Jemy Varghese, Vinh Dang, Jeremy Morrissette, Joseph A. Fraietta, Caroline Diorio, Janis K, Burkhardt, Scott Canna
Journal: Journal of Human Immunity
Series: CIS Meeting Abstracts 2025
J Hum Immun (2025) 1 (CIS2025): CIS2025abstract.41.
https://doi.org/10.70962/CIS2025abstract.41
Published: 25 April 2025
View article titled, Dissecting the HLH Immune Synapse: Critical Roles for Termination, Cytokine Intensity, and Target Cell Death
Journal Articles

Lymphocyte egress signal sphingosine-1-phosphate promotes ERM-guided, bleb-based migration

In Special Collection:
Immune Cell Biology 2022
Tanner F. Robertson, Pragati Chengappa, Daniela Gomez Atria, Christine F. Wu, Lyndsay Avery, Nathan H. Roy, Ivan Maillard, Ryan J. Petrie, Janis K. Burkhardt
Journal: Journal of Cell Biology
J Cell Biol (2021) 220 (6): e202007182.
https://doi.org/10.1083/jcb.202007182
Published: 25 March 2021
View article titled, Lymphocyte egress signal sphingosine-1-phosphate promotes ERM-guided, bleb-based migration
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Journal Articles

Multiple actin networks coordinate mechanotransduction at the immunological synapse

In Special Collection:
Immune Cell Biology 2020
Daniel Blumenthal, Janis K. Burkhardt
Journal: Journal of Cell Biology
J Cell Biol (2020) 219 (2): e201911058.
https://doi.org/10.1083/jcb.201911058
Published: 24 January 2020
View article titled, Multiple actin networks coordinate mechanotransduction at the immunological synapse
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Journal Articles

The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobility

William A. Comrie, Shuixing Li, Sarah Boyle, Janis K. Burkhardt
Journal: Journal of Cell Biology
J Cell Biol (2015) 208 (4): 457–473.
https://doi.org/10.1083/jcb.201406120
Published: 09 February 2015
View article titled, The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobility
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Includes: Supplementary data
Journal Articles

F-actin flow drives affinity maturation and spatial organization of LFA-1 at the immunological synapse

William A. Comrie, Alexander Babich, Janis K. Burkhardt
Journal: Journal of Cell Biology
J Cell Biol (2015) 208 (4): 475–491.
https://doi.org/10.1083/jcb.201406121
Published: 09 February 2015
View article titled, F-actin flow drives affinity maturation and spatial organization of LFA-1 at the immunological synapse
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Includes: Supplementary data
Journal Articles

F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation

Alexander Babich, Shuixing Li, Roddy S. O'Connor, Michael C. Milone, Bruce D. Freedman, Janis K. Burkhardt
Journal: Journal of Cell Biology
J Cell Biol (2012) 197 (6): 775–787.
https://doi.org/10.1083/jcb.201201018
Published: 04 June 2012
View article titled, F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation
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Includes: Multimedia, Supplementary data
Journal Articles

CD43 Regulation of T Cell Activation Is Not through Steric Inhibition of T Cell–APC Interactions but through an Intracellular Mechanism

Jiankun Tong, Eric J. Allenspach, Stephenie M. Takahashi, Purvi D. Mody, Chan Park, Janis K. Burkhardt, Anne I. Sperling
Journal: Journal of Experimental Medicine
J Exp Med (2004) 199 (9): 1277–1283.
https://doi.org/10.1084/jem.20021602
Published: 26 April 2004
View article titled, CD43 Regulation of T Cell Activation Is Not through Steric Inhibition of T Cell–APC Interactions but through an Intracellular Mechanism
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Includes: Supplementary data
Journal Articles

Overexpression of the Dynamitin (p50) Subunit of the Dynactin Complex Disrupts Dynein-dependent Maintenance of Membrane Organelle Distribution

Janis K. Burkhardt, Christophe J. Echeverri, Tommy Nilsson, Richard B. Vallee
Journal: Journal of Cell Biology
J Cell Biol (1997) 139 (2): 469–484.
https://doi.org/10.1083/jcb.139.2.469
Published: 20 October 1997
View article titled, Overexpression of the Dynamitin (p50) Subunit of the Dynactin Complex Disrupts Dynein-dependent Maintenance of Membrane Organelle Distribution
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Journal Articles

Molecular Requirements for Bi-directional Movement of Phagosomes Along Microtubules

Ariel Blocker, Fedor F. Severin, Janis K. Burkhardt, James B. Bingham, Hanry Yu, Jean-Christophe Olivo, Trina A. Schroer, Anthony A. Hyman, Gareth Griffiths
Journal: Journal of Cell Biology
J Cell Biol (1997) 137 (1): 113–129.
https://doi.org/10.1083/jcb.137.1.113
Published: 07 April 1997
View article titled, Molecular Requirements for Bi-directional Movement of Phagosomes Along Microtubules
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Journal Articles

Membrane Tumor Necrosis Factor (TNF) Induced Cooperative Signaling of TNFR60 and TNFR80 Favors Induction of Cell Death Rather Than Virus Production in HIV-infected T Cells

Janis K. Lazdins, Matthias Grell, Maja R. Walker, Kathie Woods-Cook, Peter Scheurich, Klaus Pfizenmaier
Journal: Journal of Experimental Medicine
J Exp Med (1997) 185 (1): 81–90.
https://doi.org/10.1084/jem.185.1.81
Published: 01 January 1997
View article titled, Membrane Tumor Necrosis Factor (TNF) Induced Cooperative Signaling of TNFR60 and TNFR80 Favors Induction of Cell Death Rather Than Virus Production in HIV-infected T Cells
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