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Gillian M. Griffiths
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Journal Articles

Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency

In Special Collection:
Genes and Immunity , Tissue Microenvironment and Immune Memory
Elena Blanco, Carme Camps, Sameer Bahal, Mohit D. Kerai, Matteo P. Ferla, Adam M. Rochussen, Adam E. Handel, Zainab M. Golwala, Helena Spiridou Goncalves, Susanne Kricke, Fabian Klein, Fang Zhang, Federica Zinghirino, Grace Evans, Thomas M. Keane, Sabrina Lizot, Maaike A.A. Kusters, Mildred A. Iro, Sanjay V. Patel, Emma C. Morris, Siobhan O. Burns, Ruth Radcliffe, Pradeep Vasudevan, Arthur Price, Olivia Gillham, Gabriel E. Valdebenito, Grant S. Stewart, Austen Worth, Stuart P. Adams, Michael Duchen, Isabelle André, David J. Adams, Giorgia Santili, Kimberly C. Gilmour, Georg A. Holländer, E. Graham Davies, Jenny C. Taylor, Gillian M. Griffiths, Adrian J. Thrasher, Fatima Dhalla, Alexandra Y. Kreins
Journal: Journal of Experimental Medicine
J Exp Med (2024) 222 (1): e20220979.
https://doi.org/10.1084/jem.20220979
Published: 19 November 2024
View article titled, Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency
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Includes: Supplementary data
Journal Articles

Signal strength controls the rate of polarization within CTLs during killing

In Special Collection:
Immune Cell Biology 2022
Gordon L. Frazer, Christian M. Gawden-Bone, Nele M.G. Dieckmann, Yukako Asano, Gillian M. Griffiths
Journal: Journal of Cell Biology
J Cell Biol (2021) 220 (10): e202104093.
https://doi.org/10.1083/jcb.202104093
Published: 22 July 2021
View article titled, Signal strength controls the rate of polarization within CTLs during killing
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Journal Articles

Teasing out function from morphology: Similarities between primary cilia and immune synapses

In Special Collection:
Immune Cell Biology 2022
Tiphaine Douanne, Jane C. Stinchcombe, Gillian M. Griffiths
Journal: Journal of Cell Biology
J Cell Biol (2021) 220 (6): e202102089.
https://doi.org/10.1083/jcb.202102089
Published: 06 May 2021
View article titled, Teasing out function from morphology: Similarities between primary cilia and immune synapses
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Journal Articles

Centrosome docking at the immunological synapse is controlled by Lck signaling

Andy Tsun, Ihjaaz Qureshi, Jane C. Stinchcombe, Misty R. Jenkins, Maike de la Roche, Joanna Kleczkowska, Rose Zamoyska, Gillian M. Griffiths
Journal: Journal of Cell Biology
J Cell Biol (2011) 192 (4): 663–674.
https://doi.org/10.1083/jcb.201008140
Published: 21 February 2011
View article titled, Centrosome docking at the immunological synapse is controlled by Lck signaling
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Includes: Supplementary data
Journal Articles

The immunological synapse: a focal point for endocytosis and exocytosis

Gillian M. Griffiths, Andy Tsun, Jane C. Stinchcombe
Journal: Journal of Cell Biology
J Cell Biol (2010) 189 (3): 399–406.
https://doi.org/10.1083/jcb.201002027
Published: 03 May 2010
View article titled, The immunological synapse: a focal point for endocytosis and exocytosis
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Includes: Multimedia, Supplementary data
Journal Articles

The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation

Corinna McCarthy, Dawn Shepherd, Sebastian Fleire, Victoria S. Stronge, Michael Koch, Petr A. Illarionov, Giovanna Bossi, Mariolina Salio, Galit Denkberg, Faye Reddington, Andrea Tarlton, B. Gopal Reddy, Richard R. Schmidt, Yoram Reiter, Gillian M. Griffiths, P. Anton van der Merwe, Gurdyal S. Besra, E. Yvonne Jones, Facundo D. Batista, Vincenzo Cerundolo
Journal: Journal of Experimental Medicine
J Exp Med (2007) 204 (5): 1131–1144.
https://doi.org/10.1084/jem.20062342
Published: 07 May 2007
View article titled, The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation
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Includes: Supplementary data
Journal Articles

Endocytosing the death sentence

Gillian M. Griffiths
Journal: Journal of Cell Biology
J Cell Biol (2003) 160 (2): 155–156.
https://doi.org/10.1083/jcb.200212143
Published: 21 January 2003
View article titled, Endocytosing the death sentence
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Journal Articles

Rab27a Is Required for Regulated Secretion in Cytotoxic T Lymphocytes

In Special Collection:
JCB65: Trafficking and Organelles
Jane C. Stinchcombe, Duarte C. Barral, Emilie H. Mules, Sarah Booth, Alistair N. Hume, Laura M. Machesky, Miguel C. Seabra, Gillian M. Griffiths
Journal: Journal of Cell Biology
J Cell Biol (2001) 152 (4): 825–834.
https://doi.org/10.1083/jcb.152.4.825
Published: 20 February 2001
View article titled, Rab27a Is Required for Regulated Secretion in Cytotoxic T Lymphocytes
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Journal Articles

Regulated Secretion from Hemopoietic Cells

Jane C. Stinchcombe, Gillian M. Griffiths
Journal: Journal of Cell Biology
J Cell Biol (1999) 147 (1): 1–5.
https://doi.org/10.1083/jcb.147.1.1
Published: 04 October 1999
View article titled, Regulated Secretion from Hemopoietic Cells
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