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Douglas R. Green
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Journal Articles

Necroptosis restricts influenza A virus as a stand-alone cell death mechanism

Maria Shubina, Bart Tummers, David F. Boyd, Ting Zhang, Chaoran Yin, Avishekh Gautam, Xi-zhi J. Guo, Diego A. Rodriguez, William J. Kaiser, Peter Vogel, Douglas R. Green, Paul G. Thomas, Siddharth Balachandran
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (11): e20191259.
https://doi.org/10.1084/jem.20191259
Published: 14 August 2020
View article titled, Necroptosis restricts influenza A virus as a stand-alone cell death mechanism
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Journal Articles

RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense

In Special Collection:
Cytokines 2018 , JEM Immunology Collection 2018 , Regulation and Dysregulation of Innate Immunity in Disease , Cell Death, Inflammation, and Adaptation to Tissue Stress
Lance W. Peterson, Naomi H. Philip, Alexandra DeLaney, Meghan A. Wynosky-Dolfi, Kendra Asklof, Falon Gray, Ruth Choa, Elisabet Bjanes, Elisabeth L. Buza, Baofeng Hu, Christopher P. Dillon, Douglas R. Green, Scott B. Berger, Peter J. Gough, John Bertin, Igor E. Brodsky
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (11): 3171–3182.
https://doi.org/10.1084/jem.20170347
Published: 30 August 2017
View article titled, RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense
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Includes: Supplementary data
Journal Articles

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

Lewis Z. Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R. Green, Hongbo Chi
Journal: Journal of Experimental Medicine
J Exp Med (2011) 208 (7): 1367–1376.
https://doi.org/10.1084/jem.20110278
Published: 27 June 2011
View article titled, HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
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Includes: Supplementary data
Journal Articles

Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation

Clare L. Scott, Martin Schuler, Vanessa S. Marsden, Alex Egle, Marc Pellegrini, Dobrila Nesic, Steve Gerondakis, Stephen L. Nutt, Douglas R. Green, Andreas Strasser
Journal: Journal of Cell Biology
J Cell Biol (2004) 164 (1): 89–96.
https://doi.org/10.1083/jcb.200310041
Published: 05 January 2004
View article titled, Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation
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Includes: Supplementary data
Journal Articles

Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis

In Special Collection:
JCB65: Cell Death
Jean-Ehrland Ricci, Roberta A. Gottlieb, Douglas R. Green
Journal: Journal of Cell Biology
J Cell Biol (2003) 160 (1): 65–75.
https://doi.org/10.1083/jcb.200208089
Published: 06 January 2003
View article titled, Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis
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Journal Articles

The role of ARK in stress-induced apoptosis in Drosophila cells

Katja C. Zimmermann, Jean-Ehrland Ricci, Nathalie M. Droin, Douglas R. Green
Journal: Journal of Cell Biology
J Cell Biol (2002) 156 (6): 1077–1087.
https://doi.org/10.1083/jcb.20112068
Published: 11 March 2002
View article titled, The role of ARK in stress-induced apoptosis in Drosophila cells
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Journal Articles

Cytochrome C Maintains Mitochondrial Transmembrane Potential and Atp Generation after Outer Mitochondrial Membrane Permeabilization during the Apoptotic Process

Nigel J. Waterhouse, Joshua C. Goldstein, Oliver von Ahsen, Martin Schuler, Donald D. Newmeyer, Douglas R. Green
Journal: Journal of Cell Biology
J Cell Biol (2001) 153 (2): 319–328.
https://doi.org/10.1083/jcb.153.2.319
Published: 16 April 2001
View article titled, Cytochrome C Maintains Mitochondrial Transmembrane Potential and Atp Generation after Outer Mitochondrial Membrane Permeabilization during the Apoptotic Process
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Journal Articles

Granzyme B–Mediated Cytochrome C Release Is Regulated by the Bcl-2 Family Members Bid and Bax

Jeffrey A. Heibein, Ing Swie Goping, Michele Barry, Michael J. Pinkoski, Gordon C. Shore, Douglas R. Green, R. Chris Bleackley
Journal: Journal of Experimental Medicine
J Exp Med (2000) 192 (10): 1391–1402.
https://doi.org/10.1084/jem.192.10.1391
Published: 13 November 2000
View article titled, Granzyme B–Mediated Cytochrome C Release Is Regulated by the Bcl-2 Family Members Bid and Bax
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Journal Articles

Changes in Endoplasmic Reticulum Luminal Environment Affect Cell Sensitivity to Apoptosis

Kimitoshi Nakamura, Ella Bossy-Wetzel, Kimberly Burns, Marc P. Fadel, Mira Lozyk, Ing Swie Goping, Michal Opas, R. Chris Bleackley, Douglas R. Green, Marek Michalak
Journal: Journal of Cell Biology
J Cell Biol (2000) 150 (4): 731–740.
https://doi.org/10.1083/jcb.150.4.731
Published: 21 August 2000
View article titled, Changes in Endoplasmic Reticulum Luminal Environment Affect Cell Sensitivity to Apoptosis
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Journal Articles

Apoptosis and Sphingomyelin Hydrolysis: The Flip Side

Douglas R. Green
Journal: Journal of Cell Biology
J Cell Biol (2000) 150 (1): F5–F8.
https://doi.org/10.1083/jcb.150.1.F5
Published: 10 July 2000
View article titled, Apoptosis and Sphingomyelin Hydrolysis: The Flip Side
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Journal Articles

The Pro-Apoptotic Proteins, Bid and Bax, Cause a Limited Permeabilization of the Mitochondrial Outer Membrane That Is Enhanced by Cytosol

Ruth M. Kluck, Mauro Degli Esposti, Guy Perkins, Christian Renken, Tomomi Kuwana, Ella Bossy-Wetzel, Martin Goldberg, Terry Allen, Michael J. Barber, Douglas R. Green, Donald D. Newmeyer
Journal: Journal of Cell Biology
J Cell Biol (1999) 147 (4): 809–822.
https://doi.org/10.1083/jcb.147.4.809
Published: 15 November 1999
View article titled, The Pro-Apoptotic Proteins, Bid and Bax, Cause a Limited Permeabilization of the Mitochondrial Outer Membrane That Is Enhanced by Cytosol
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Journal Articles

Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner

In Special Collection:
JCB65: Cell Death
Elizabeth A. Slee, Mary T. Harte, Ruth M. Kluck, Beni B. Wolf, Carlos A. Casiano, Donald D. Newmeyer, Hong-Gang Wang, John C. Reed, Donald W. Nicholson, Emad S. Alnemri, Douglas R. Green, Seamus J. Martin
Journal: Journal of Cell Biology
J Cell Biol (1999) 144 (2): 281–292.
https://doi.org/10.1083/jcb.144.2.281
Published: 25 January 1999
View article titled, Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner
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Journal Articles

Transforming Growth Factor β1 Inhibits Fas Ligand Expression and Subsequent Activation-induced Cell Death in T Cells via Downregulation of c-Myc

Laurent Genestier, Shailaja Kasibhatla, Thomas Brunner, Douglas R. Green
Journal: Journal of Experimental Medicine
J Exp Med (1999) 189 (2): 231–239.
https://doi.org/10.1084/jem.189.2.231
Published: 18 January 1999
View article titled, Transforming Growth Factor β1 Inhibits Fas Ligand Expression and Subsequent Activation-induced Cell Death in T Cells via Downregulation of c-Myc
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