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Benjamin Haley
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Journal Articles

Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage

In Special Collection:
JEM Immunology Collection 2024 , Immunology Update Winter 2024 , Innate Immune Signaling: From Host Defense to Disease Pathogenesis
Ann-Jay Tong, Rebecca Leylek, Anna-Maria Herzner, Diamanda Rigas, Sara Wichner, Craig Blanchette, Siri Tahtinen, Christopher C. Kemball, Ira Mellman, Benjamin Haley, Emily C. Freund, Lélia Delamarre
Journal: Journal of Experimental Medicine
J Exp Med (2023) 221 (2): e20230341.
https://doi.org/10.1084/jem.20230341
Published: 14 December 2023
View article titled, Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage
Open the PDF for Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage in another window
Includes: Supplementary data
Journal Articles

High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA

Soyoung A. Oh, Kate Senger, Shravan Madireddi, Ilseyar Akhmetzyanova, Isabel E. Ishizuka, Somayeh Tarighat, Jerry H. Lo, David Shaw, Benjamin Haley, Sascha Rutz
Journal: Journal of Experimental Medicine
J Exp Med (2022) 219 (5): e20211530.
https://doi.org/10.1084/jem.20211530
Published: 22 April 2022
View article titled, High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA
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Includes: Supplementary data
Journal Articles

ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses

Anna-Maria Herzner, Zia Khan, Eric L. Van Nostrand, Sara Chan, Trinna Cuellar, Ronald Chen, Ximo Pechuan-Jorge, Laszlo Komuves, Margaret Solon, Zora Modrusan, Benjamin Haley, Gene W. Yeo, Timothy W. Behrens, Matthew L. Albert
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (9): e20201833.
https://doi.org/10.1084/jem.20201833
Published: 23 July 2021
View article titled, ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses
Open the PDF for ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses in another window
Includes: Supplementary data
Journal Articles

UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD

Danming Tang, Wendy Sandoval, Cynthia Lam, Benjamin Haley, Peter Liu, Di Xue, Deepankar Roy, Tom Patapoff, Salina Louie, Brad Snedecor, Shahram Misaghi
Journal: Journal of Cell Biology
J Cell Biol (2020) 219 (7): e201908087.
https://doi.org/10.1083/jcb.201908087
Published: 17 June 2020
View article titled, UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD
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Journal Articles

Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9

Emily C. Freund, Jaclyn Y. Lock, Jaehak Oh, Timurs Maculins, Lelia Delamarre, Christopher J. Bohlen, Benjamin Haley, Aditya Murthy
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (7): e20191692.
https://doi.org/10.1084/jem.20191692
Published: 01 May 2020
View article titled, Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9
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Includes: Supplementary data
Journal Articles

Mutation position is an important determinant for predicting cancer neoantigens

In Special Collection:
JEM 2020 Update on Cancer Immunology and Immunotherapy , JEM Cancer Collection 2020 , JEM Cancer Collection 2021
Aude-Hélène Capietto, Suchit Jhunjhunwala, Samuel B. Pollock, Patrick Lupardus, Jim Wong, Lena Hänsch, James Cevallos, Yajun Chestnut, Ajay Fernandez, Nicolas Lounsbury, Tamaki Nozawa, Manmeet Singh, Zhiyuan Fan, Cecile C. de la Cruz, Qui T. Phung, Lucia Taraborrelli, Benjamin Haley, Jennie R. Lill, Ira Mellman, Richard Bourgon, Lélia Delamarre
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (4): e20190179.
https://doi.org/10.1084/jem.20190179
Published: 15 January 2020
View article titled, Mutation position is an important determinant for predicting cancer neoantigens
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Includes: Supplementary data
Journal Articles

SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer

In Special Collection:
Cancer Plasticity and Heterogeneity , Cell Biology of Cancer 2018
Manuel Viotti, Catherine Wilson, Mark McCleland, Hartmut Koeppen, Benjamin Haley, Suchit Jhunjhunwala, Christiaan Klijn, Zora Modrusan, David Arnott, Marie Classon, Jean-Philippe Stephan, Ira Mellman
Journal: Journal of Cell Biology
J Cell Biol (2017) 217 (2): 763–777.
https://doi.org/10.1083/jcb.201705031
Published: 11 December 2017
View article titled, SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer
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Includes: Supplementary data
Journal Articles

­­­Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia­­

In Special Collection:
Mitochondria and Autophagy 2018 , Nuclear Organization and Function 2018 , Cell Biology of Infection and the Immune Response 2018
Trinna L. Cuellar, Anna-Maria Herzner, Xiaotian Zhang, Yogesh Goyal, Colin Watanabe, Brad A. Friedman, Vasantharajan Janakiraman, Steffen Durinck, Jeremy Stinson, David Arnott, Tommy K. Cheung, Subhra Chaudhuri, Zora Modrusan, Jonas Martin Doerr, Marie Classon, Benjamin Haley
Journal: Journal of Cell Biology
J Cell Biol (2017) 216 (11): 3535–3549.
https://doi.org/10.1083/jcb.201612160
Published: 08 September 2017
View article titled, ­­­Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia­­
Open the PDF for ­­­Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia­­ in another window
Includes: Supplementary data