Chloride Channels and Transporters
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Journal Articles

Locking the TMEM16A chloride channel into its conductive state

Zhang Feng
Journal: Journal of General Physiology
Series: Chloride Channels and Transporters
J Gen Physiol (2026) 158 (5): e202614052.
https://doi.org/10.1085/jgp.202614052
Published: 30 July 2026
View article titled, Locking the TMEM16A chloride channel into its conductive state
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Journal Articles

Conformational changes upon pore blocker removal reveal conductive states of TMEM16A

Christina A. Stephens, Frank V. Marcoline, Christian J. Peters, Michael Grabe
Journal: Journal of General Physiology
Series: Chloride Channels and Transporters
J Gen Physiol (2026) 158 (5): e202513961.
https://doi.org/10.1085/jgp.202513961
Published: 02 July 2026
View article titled, Conformational changes upon pore blocker removal reveal conductive states of TMEM16A
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Includes: Supplementary data
Journal Articles

Mechanistic insights into DCPIB inhibition of VRAC: Electrostatic control and binding plasticity

Héctor Gaitán-Peñas, Salomé Llabrés, Marina Pedrola, Marc González-Subías, Jordi Juárez-Jiménez, Michael Pusch, Rodolfo Lavilla, Raúl Estévez
Journal: Journal of General Physiology
Series: Chloride Channels and Transporters
J Gen Physiol (2026) 158 (5): e202513953.
https://doi.org/10.1085/jgp.202513953
Published: 25 June 2026
View article titled, Mechanistic insights into DCPIB inhibition of VRAC: Electrostatic control and binding plasticity
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Includes: Supplementary data
Journal Articles

Regulation of olfactory chloride and cyclic nucleotide–gated channels by cholesterol

Samsudeen Ponissery Saidu, Alexander Kross, Michele Dibattista, Katharina Gaus, Johannes Reisert
Journal: Journal of General Physiology
Series: Chloride Channels and Transporters
J Gen Physiol (2026) 158 (4): e202513963.
https://doi.org/10.1085/jgp.202513963
Published: 23 June 2026
View article titled, Regulation of olfactory chloride and cyclic nucleotide–gated channels by cholesterol
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Journal Articles

Model of ocular surface ion and water transport predicts efficacy of dry eye therapeutics

Varun Verma, Ethan S. Lindgren, Marc H. Levin, Onur Cil, Lukmanee Tradtrantip, Rongshan Yan, Neel D. Pasricha, Alan S. Verkman
Journal: Journal of General Physiology
Series: Chloride Channels and Transporters
J Gen Physiol (2026) 158 (4): e202513958.
https://doi.org/10.1085/jgp.202513958
Published: 22 May 2026
View article titled, Model of ocular surface ion and water transport predicts efficacy of dry eye therapeutics
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