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Journal Articles

Constitutive assembly of Ca2+ entry units in soleus muscle from calsequestrin knockout mice

Antonio Michelucci, Laura Pietrangelo, Giorgia Rastelli, Feliciano Protasi, Robert T. Dirksen, Simona Boncompagni
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2022) 154 (12): e202213114.
https://doi.org/10.1085/jgp.202213114
Published: 12 October 2022
View article titled, Constitutive assembly of Ca2+ entry units in soleus muscle from calsequestrin knockout mice
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Includes: Supplementary data
Journal Articles

Excitation–contraction coupling in cardiac, skeletal, and smooth muscle

Robert T. Dirksen, David A. Eisner, Eduardo Ríos, Karin R. Sipido
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2022) 154 (9): e202213244.
https://doi.org/10.1085/jgp.202213244
Published: 19 August 2022
View article titled, Excitation–contraction coupling in cardiac, skeletal, and smooth muscle
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Includes: Supplementary data
Journal Articles

Postdevelopmental knockout of Orai1 improves muscle pathology in a mouse model of Duchenne muscular dystrophy

Maricela García-Castañeda, Antonio Michelucci, Nan Zhao, Sundeep Malik, Robert T. Dirksen
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2022) 154 (9): e202213081.
https://doi.org/10.1085/jgp.202213081
Published: 08 August 2022
View article titled, Postdevelopmental knockout of Orai1 improves muscle pathology in a mouse model of Duchenne muscular dystrophy
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Includes: Supplementary data
Journal Articles

Acute exposure to extracellular BTP2 does not inhibit Ca2+ release during EC coupling in intact skeletal muscle fibers

Lan Wei-LaPierre, Linda Groom, Robert T. Dirksen
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2021) 154 (9): e202112976.
https://doi.org/10.1085/jgp.202112976
Published: 15 December 2021
View article titled, Acute exposure to extracellular BTP2 does not inhibit Ca2+ release during EC coupling in intact skeletal muscle fibers
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Journal Articles

Exercise attenuates juvenile irradiation-induced skeletal muscle decline by improving calcium handling and decreasing mitochondrial stress: Calcium Signaling and Excitation–Contraction in Cardiac, Skeletal and Smooth Muscle

Thomas N. O’Connor, Jacob G. Kallenbach, Robert T. Dirksen, Joe V. Chakkalakal
Journal: Journal of General Physiology
Series: E–C Coupling Meeting 2021
J Gen Physiol (2021) 154 (9): e2021ecc21.
https://doi.org/10.1085/jgp.2021ecc21
Published: 12 November 2021
View article titled, Exercise attenuates juvenile irradiation-induced skeletal muscle decline by improving calcium handling and decreasing mitochondrial stress: Calcium Signaling and Excitation–Contraction in Cardiac, Skeletal and Smooth Muscle
Journal Articles

Pre-assembled Ca2+ entry units and constitutively active Ca2+ entry in skeletal muscle of calsequestrin-1 knockout mice

Antonio Michelucci, Simona Boncompagni, Laura Pietrangelo, Takahiro Takano, Feliciano Protasi, Robert T. Dirksen
Journal: Journal of General Physiology
J Gen Physiol (2020) 152 (10): e202012617.
https://doi.org/10.1085/jgp.202012617
Published: 05 August 2020
View article titled, Pre-assembled Ca2+ entry units and constitutively active Ca2+ entry in skeletal muscle of calsequestrin-1 knockout mice
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Journal Articles

Biophysical mechanisms for QRS- and QTc-interval prolongation in mice with cardiac expression of expanded CUG-repeat RNA

In Special Collection:
Cardiac Physiology 2021
Kevin M. Tylock, David S. Auerbach, Zhen Zhi Tang, Charles A. Thornton, Robert T. Dirksen
Journal: Journal of General Physiology
J Gen Physiol (2020) 152 (2): e201912450.
https://doi.org/10.1085/jgp.201912450
Published: 22 January 2020
View article titled, Biophysical mechanisms for QRS- and QTc-interval prolongation in mice with cardiac expression of expanded CUG-repeat RNA
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Journal Articles

Isolating a reverse-mode ATP synthase–dependent mechanism of mitoflash activation

Lan Wei-LaPierre, Robert T. Dirksen
Journal: Journal of General Physiology
J Gen Physiol (2019) 151 (6): 708–713.
https://doi.org/10.1085/jgp.201912358
Published: 22 April 2019
View article titled, Isolating a reverse-mode ATP synthase–dependent mechanism of mitoflash activation
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Journal Articles

Trojan triplets: RNA-based pathomechanisms for muscle dysfunction in Huntington’s disease

Martin Skov, Robert T. Dirksen
Journal: Journal of General Physiology
J Gen Physiol (2016) 149 (1): 49–53.
https://doi.org/10.1085/jgp.201611728
Published: 09 December 2016
View article titled, Trojan triplets: RNA-based pathomechanisms for muscle dysfunction in Huntington’s disease
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Journal Articles

New method for determining total calcium content in tissue applied to skeletal muscle with and without calsequestrin

Cédric R.H. Lamboley, Sandrine A. Kake Guena, Fatou Touré, Camille Hébert, Louiza Yaddaden, Stephanie Nadeau, Patrice Bouchard, Lan Wei-LaPierre, Jean Lainé, Eric C. Rousseau, Jérôme Frenette, Feliciano Protasi, Robert T. Dirksen, Paul C. Pape
Journal: Journal of General Physiology
J Gen Physiol (2015) 145 (2): 127–153.
https://doi.org/10.1085/jgp.201411250
Published: 26 January 2015
View article titled, New method for determining total calcium content in tissue applied to skeletal muscle with and without calsequestrin
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Includes: Supplementary data
Journal Articles

Mitochondria take center stage

Shey-Shing Sheu, Robert T. Dirksen, Edward N. Pugh, Jr.
Journal: Journal of General Physiology
Series: Perspectives on: SGP Symposium on Mitochondrial Physiology and Medicine
J Gen Physiol (2012) 139 (6): 391–393.
https://doi.org/10.1085/jgp.201210819
Published: 28 May 2012
View article titled, Mitochondria take center stage
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Journal Articles

Mitochondrial superoxide flashes: From discovery to new controversies

Lan Wei, Robert T. Dirksen
Journal: Journal of General Physiology
Series: Perspectives on: SGP Symposium on Mitochondrial Physiology and Medicine
J Gen Physiol (2012) 139 (6): 425–434.
https://doi.org/10.1085/jgp.201210790
Published: 28 May 2012
View article titled, Mitochondrial superoxide flashes: From discovery to new controversies
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Journal Articles

The 65th Symposium of the Society for General Physiologists: Energizing research in mitochondrial physiology and medicine

Shey-Shing Sheu, Robert T. Dirksen, Edward N. Pugh, Jr.
Journal: Journal of General Physiology
J Gen Physiol (2011) 138 (6): 563–567.
https://doi.org/10.1085/jgp.201110739
Published: 28 November 2011
View article titled, The 65th Symposium of the Society for General Physiologists: Energizing research in mitochondrial physiology and medicine
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Journal Articles

Response to the letter: “On the localization of ClC-1 in skeletal muscle fibers”

John D. Lueck, Ann E. Rossi, Charles A. Thornton, Kevin P. Campbell, Robert T. Dirksen
Journal: Journal of General Physiology
J Gen Physiol (2011) 137 (3): 331–333.
https://doi.org/10.1085/jgp.201010589
Published: 28 February 2011
View article titled, Response to the letter: “On the localization of ClC-1 in skeletal muscle fibers”
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Journal Articles

Muscle weakness in Ryr1I4895T/WT knock-in mice as a result of reduced ryanodine receptor Ca2+ ion permeation and release from the sarcoplasmic reticulum

Ryan E. Loy, Murat Orynbayev, Le Xu, Zoita Andronache, Simona Apostol, Elena Zvaritch, David H. MacLennan, Gerhard Meissner, Werner Melzer, Robert T. Dirksen
Journal: Journal of General Physiology
J Gen Physiol (2010) 137 (1): 43–57.
https://doi.org/10.1085/jgp.201010523
Published: 13 December 2010
View article titled, Muscle weakness in Ryr1I4895T/WT knock-in mice as a result of reduced ryanodine receptor Ca2+ ion permeation and release from the sarcoplasmic reticulum
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Includes: Supplementary data
Journal Articles

Sarcolemmal-restricted localization of functional ClC-1 channels in mouse skeletal muscle

John D. Lueck, Ann E. Rossi, Charles A. Thornton, Kevin P. Campbell, Robert T. Dirksen
Journal: Journal of General Physiology
J Gen Physiol (2010) 136 (6): 597–613.
https://doi.org/10.1085/jgp.201010526
Published: 15 November 2010
View article titled, Sarcolemmal-restricted localization of functional ClC-1 channels in mouse skeletal muscle
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Includes: Supplementary data
Journal Articles

Emerging questions about the macromolecular machines of muscle

Robert T. Dirksen, Edward N. Pugh, Jr.
Journal: Journal of General Physiology
Series: Perspectives on: SGP Symposium on Muscle in Health and Disease
J Gen Physiol (2010) 136 (1): 3–5.
https://doi.org/10.1085/jgp.201010481
Published: 28 June 2010
View article titled, Emerging questions about the macromolecular machines of muscle
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Journal Articles

The 63rd Symposium of the Society of General Physiologists: “muscles” instead of squid at Woods Hole

Robert T. Dirksen, Roger A. Bannister
Journal: Journal of General Physiology
J Gen Physiol (2009) 134 (6): 453–455.
https://doi.org/10.1085/jgp.200910363
Published: 30 November 2009
View article titled, The 63rd Symposium of the Society of General Physiologists: “muscles” instead of squid at Woods Hole
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Journal Articles

Triadin Binding to the C-Terminal Luminal Loop of the Ryanodine Receptor is Important for Skeletal Muscle Excitation–Contraction Coupling

Sanjeewa A. Goonasekera, Nicole A. Beard, Linda Groom, Takashi Kimura, Alla D. Lyfenko, Andrew Rosenfeld, Isabelle Marty, Angela F. Dulhunty, Robert T. Dirksen
Journal: Journal of General Physiology
J Gen Physiol (2007) 130 (4): 365–378.
https://doi.org/10.1085/jgp.200709790
Published: 10 September 2007
View article titled, Triadin Binding to the C-Terminal Luminal Loop of the Ryanodine Receptor is Important for Skeletal Muscle Excitation–Contraction Coupling
Open the PDF for Triadin Binding to the C-Terminal Luminal Loop of the Ryanodine Receptor is Important for Skeletal Muscle Excitation–Contraction Coupling in another window
Journal Articles

Muscle Chloride Channel Dysfunction in Two Mouse Models of Myotonic Dystrophy

John D. Lueck, Ami Mankodi, Maurice S. Swanson, Charles A. Thornton, Robert T. Dirksen
Journal: Journal of General Physiology
J Gen Physiol (2006) 129 (1): 79–94.
https://doi.org/10.1085/jgp.200609635
Published: 11 December 2006
View article titled, Muscle Chloride Channel Dysfunction in Two Mouse Models of Myotonic Dystrophy
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