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Ion Channel Structure & Function 2018

With and relevance to the 4th Annual Meeting of the Biophysical Society of Canada, this collection features groundbreaking research on the structure-function relationships of ion channels.

Article

Zn²⁺-dependent conformational coupling in Hv1

Victor De La Rosa; Ashley L. Bennett; Ian Scott Ramsey

https://doi.org/10.1085/jgp.201711822

Article

His¹⁶⁸ is an internal pH sensor of hH_V1

Vladimir V. Cherny; Deri Morgan; Sarah Thomas; Susan M.E. Smith; Thomas E. DeCoursey

https://doi.org/10.1085/jgp.201711968

Article

Ligand-induced structural rearrangements in TRPA1

Amrita Samanta; Janna Kiselar; Ruth A. Pumroy; Seungil Han; Vera Y. Moiseenkova-Bell

https://doi.org/10.1085/jgp.201711876

Review

Cryo-EM structures of K_ATP channels

Michael C. Puljung

https://doi.org/10.1085/jgp.201711978

Article

Different agonists evoke distinct structural changes

Nuriya Mukhtasimova; Steven M. Sine

https://doi.org/10.1085/jgp.201711881

Article

Altered fast and slow gating elicited by Cx26G12R

Isaac E. García; Felipe Villanelo; Gustavo F. Contreras; Amaury Pupo; Bernardo I. Pinto; Jorge E. Contreras; Tomás Pérez-Acle; Osvaldo Alvarez; Ramon Latorre; Agustín D. Martínez; Carlos González

https://doi.org/10.1085/jgp.201711782

Review

Functional anatomy of CFTR

Tzyh-Chang Hwang; Jiunn-Tyng Yeh; Jingyao Zhang; Ying-Chun Yu; Han-I Yeh; Samantha Destefano

https://doi.org/10.1085/jgp.201711946

Article

Intrinsic ligand regulates KCNH channels

Gucan Dai; Zachary M. James; William N. Zagotta

https://doi.org/10.1085/jgp.201711989

Article

Optimizing Cys-loop receptor concatenation

Philip Kiær Ahring; Vivian Wan Yu Liao; Thomas Balle