The anatomy of DNA molecules isolated from mature bacteriophage is reviewed. These molecules are linear, duplex DNA consisting mainly of uninterrupted polynucleotide chains. Certain phage (T5 and PB) contain four specifically located interruptions. While the nucleotide sequence of most of these molecules is unique (T5, T3, T7, λ), some are circular permutations of each other (T2, T4, P22). Partial degradation of these DNA molecules by exonuclease III predisposes some of them to form circles upon annealing, but indicating they are terminally redundant.
Article| July 01 1966
The Arrangement of Information in DNA Molecules
Charles A. Thomas, Jr.
From the Department of Biophysics, The Johns Hopkins University, Baltimore
Online Issn: 1540-7748
Print Issn: 0022-1295
Copyright © 1966 by The Rockefeller University Press
J Gen Physiol (1966) 49 (6): 143–169.
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Charles A. Thomas; The Arrangement of Information in DNA Molecules . J Gen Physiol 1 July 1966; 49 (6): 143–169. doi: https://doi.org/10.1085/jgp.49.6.143
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