1. The equations which serve to predict the injury of tissue in 0.52 M NaCl and in 0.278 M CaCl2 and its subsequent recovery (when it is replaced in sea water) also enable us to predict the behavior of tissue in mixtures of these solutions, as well as its recovery in sea water after exposure to mixtures.

2. The reactions which are assumed in order to account for the behavior of the tissue proceed as if they were inhibited by a salt compound formed by the union of NaCl and CaCl2 with some constituent of the protoplasm (certain of these reactions are accelerated by CaCl2).

3. In this and preceding papers a quantitative theory is developed in order to explain: (a) the toxicity of NaCl and CaCl2; (b) the antagonism between these substances; (c) the fact that recovery (in sea water) may be partial or complete, depending on the length of exposure to the toxic solution.

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