A simple theoretical model has been presented whose behavior duplicates the variation in bicarbonate ion concentration in the blood following exercise. Methods for the evaluation of the constants of rational equations to describe the concentration in muscle cells, in blood plasma, and in removal cells, of the anions produced in exercise have been devised. These methods have been applied to experimental data from 23 experiments, and a close agreement between the observed and theoretically predicted values for blood plasma has been found. From the mathematical analysis of the data values for permeability of acid anions produced in exercise have been estimated as 75 x 10–5 and 5.9 x 10–5 cm. per sec. between muscle cell and blood (extracellular fluid) and between blood plasma and removal cells respectively.
Article|
January 20 1944
A PHYSICAL THEORY OF ACID ANION DISPLACEMENT AND RECOVERY FOLLOWING EXERCISE
Manuel F. Morales
,
Manuel F. Morales
From the Division of Physiology and the Institute of Child Welfare, University of California, Berkeley
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Nathan W. Shock
Nathan W. Shock
From the Division of Physiology and the Institute of Child Welfare, University of California, Berkeley
Search for other works by this author on:
Manuel F. Morales
From the Division of Physiology and the Institute of Child Welfare, University of California, Berkeley
Nathan W. Shock
From the Division of Physiology and the Institute of Child Welfare, University of California, Berkeley
Received:
August 20 1943
Online Issn: 1540-7748
Print Issn: 0022-1295
Copyright, 1944, by The Rockefeller Institute for Medical Research
1944
J Gen Physiol (1944) 27 (3): 155–165.
Article history
Received:
August 20 1943
Citation
Manuel F. Morales, Nathan W. Shock; A PHYSICAL THEORY OF ACID ANION DISPLACEMENT AND RECOVERY FOLLOWING EXERCISE . J Gen Physiol 20 January 1944; 27 (3): 155–165. doi: https://doi.org/10.1085/jgp.27.3.155
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