In Nitella, as in Halicystis, guaiacol increases the mobility of Na+ in the outer protoplasmic surface but leaves the mobility of K+ unaffected. This differs from the situation in Valonia where the mobility of Na+ is increased and that of K+ is decreased.

The partition coefficient of Na+ in the outer protoplasmic surface is increased and that of K+ left unchanged.

Recovery after the action current is delayed in the presence of guaiacol and the action curves are "square topped."

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