Techniques developed for determining summed encoder feedback in conjunction with the leaky integrator and variable-gamma models for repetitive firing are applied to spike train data obtained from the slowly adapting crustacean stretch receptor and the eccentric cell of Limulus. Input stimuli were intracellularly applied currents. Analysis of data from cells stringently selected by reproducibility criteria gave a consistent picture for the dynamics of repetitive firing. The variable-gamma model with appropriate summed feedback was most accurate for describing encoding behavior of both cell types. The leaky integrator model, while useful for determining summed feedback parameters, was inadequate to account for underlying mechanisms of encoder activity. For the stretch receptor, two summed feedback processes were detected: one had a short time constant; the other, a long one. Appropriate tests indicated that the short time constant effect was from an electrogenic sodium pump, and the same is presumed for the long time constant summed feedback. Both feedbacks show seasonal and/or species variations. Short hyperpolarizing pulses inhibited the feedback from the long time constant process. The eccentric cell also showed two summed feedback processes: one is due to self inhibition, the other is postulated to be a short time constant electrogenic sodium pump similar to that described in the stretch receptor.
Skip Nav Destination
Article navigation
1 June 1977
Article|
June 01 1977
Repetitive firing: quantitative analysis of encoder behavior of slowly adapting stretch receptor of crayfish and eccentric cell of Limulus.
J F Fohlmeister
R E Poppele
R L Purple
Online ISSN: 1540-7748
Print ISSN: 0022-1295
J Gen Physiol (1977) 69 (6): 849–877.
Citation
J F Fohlmeister, R E Poppele, R L Purple; Repetitive firing: quantitative analysis of encoder behavior of slowly adapting stretch receptor of crayfish and eccentric cell of Limulus.. J Gen Physiol 1 June 1977; 69 (6): 849–877. doi: https://doi.org/10.1085/jgp.69.6.849
Download citation file:
Sign in
Don't already have an account? Register
Client Account
You could not be signed in. Please check your email address / username and password and try again.
Could not validate captcha. Please try again.
Sign in via your Institution
Sign in via your InstitutionSuggested Content
Interpretation of the Repetitive Firing of Nerve Cells
J Gen Physiol (July,1962)
Repetitive firing: a quantitative study of feedback in model encoders.
J Gen Physiol (June,1977)
Oscillation and Repetitive Firing in Squid Axons : Comparison of experiments with computations
J Gen Physiol (January,1970)
Email alerts
Advertisement