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Richard O. Hynes
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Journal Articles

Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses

In Special Collection:
Lymphocytes and their Roles in Cancer
Byron H. Kwan, Eric F. Zhu, Alice Tzeng, Harun R. Sugito, Ahmed A. Eltahir, Botong Ma, Mary K. Delaney, Patrick A. Murphy, Monique J. Kauke, Alessandro Angelini, Noor Momin, Naveen K. Mehta, Alecia M. Maragh, Richard O. Hynes, Glenn Dranoff, Jennifer R. Cochran, K. Dane Wittrup
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (6): 1679–1690.
https://doi.org/10.1084/jem.20160831
Published: 04 May 2017
View article titled, Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses
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Includes: Supplementary data
Journal Articles

Mena binds α5 integrin directly and modulates α5β1 function

Stephanie L. Gupton, Daisy Riquelme, Shannon K. Hughes-Alford, Jenny Tadros, Shireen S. Rudina, Richard O. Hynes, Douglas Lauffenburger, Frank B. Gertler
Journal: Journal of Cell Biology
J Cell Biol (2012) 198 (4): 657–676.
https://doi.org/10.1083/jcb.201202079
Published: 20 August 2012
View article titled, Mena binds α5 integrin directly and modulates α5β1 function
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Includes: Supplementary data
Journal Articles

The evolution of metazoan extracellular matrix

Richard O. Hynes
Journal: Journal of Cell Biology
Series: Evolution
J Cell Biol (2012) 196 (6): 671–679.
https://doi.org/10.1083/jcb.201109041
Published: 19 March 2012
View article titled, The evolution of metazoan extracellular matrix
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Journal Articles

α4β1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development

Shawdee Eshghi, Mariette G. Vogelezang, Richard O. Hynes, Linda G. Griffith, Harvey F. Lodish
Journal: Journal of Cell Biology
J Cell Biol (2008) 181 (2): 395.
https://doi.org/10.1083/jcb.20070208020080326a
Published: 21 April 2008
View article titled, α4β1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development
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Journal Articles

α4β1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development

Shawdee Eshghi, Mariette G. Vogelezang, Richard O. Hynes, Linda G. Griffith, Harvey F. Lodish
Journal: Journal of Cell Biology
J Cell Biol (2007) 177 (5): 871–880.
https://doi.org/10.1083/jcb.200702080
Published: 04 June 2007
View article titled, α4β1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development
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Journal Articles

Requirement for the NF-κB Family Member RelA in the Development of Secondary Lymphoid Organs

Elizabeth Alcamo, Nir Hacohen, Leah C. Schulte, Paul D. Rennert, Richard O. Hynes, David Baltimore
Journal: Journal of Experimental Medicine
J Exp Med (2002) 195 (2): 233–244.
https://doi.org/10.1084/jem.20011885
Published: 22 January 2002
View article titled, Requirement for the NF-κB Family Member RelA in the Development of Secondary Lymphoid Organs
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Journal Articles

The Evolution of Cell Adhesion

Richard O. Hynes, Qi Zhao
Journal: Journal of Cell Biology
J Cell Biol (2000) 150 (2): F89–F96.
https://doi.org/10.1083/jcb.150.2.F89
Published: 24 July 2000
View article titled, The Evolution of Cell Adhesion
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Journal Articles

Interaction of Dendritic Cells with Skin Endothelium: A New Perspective on Immunosurveillance

Caroline Robert, Robert C. Fuhlbrigge, J. David Kieffer, Seyoum Ayehunie, Richard O. Hynes, Guiying Cheng, Stephan Grabbe, Ulrich H. von Andrian, Thomas S. Kupper
Journal: Journal of Experimental Medicine
J Exp Med (1999) 189 (4): 627–636.
https://doi.org/10.1084/jem.189.4.627
Published: 15 February 1999
View article titled, Interaction of Dendritic Cells with Skin Endothelium: A New Perspective on Immunosurveillance
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Journal Articles

Role of P-Selectin Cytoplasmic Domain in Granular Targeting In Vivo and in Early Inflammatory Responses

Daqing W. Hartwell, Tanya N. Mayadas, Gaëtan Berger, Paul S. Frenette, Helen Rayburn, Richard O. Hynes, Denisa D. Wagner
Journal: Journal of Cell Biology
J Cell Biol (1998) 143 (4): 1129–1141.
https://doi.org/10.1083/jcb.143.4.1129
Published: 16 November 1998
View article titled, Role of P-Selectin Cytoplasmic Domain in Granular Targeting In Vivo and in Early Inflammatory Responses
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Journal Articles

Dystrophic Muscle in Mice Chimeric for Expression of α5 Integrin

Daniela Taverna, Marie-Helene Disatnik, Helen Rayburn, Roderick T. Bronson, Joy Yang, Thomas A. Rando, Richard O. Hynes
Journal: Journal of Cell Biology
J Cell Biol (1998) 143 (3): 849–859.
https://doi.org/10.1083/jcb.143.3.849
Published: 02 November 1998
View article titled, Dystrophic Muscle in Mice Chimeric for Expression of α5 Integrin
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Journal Articles

Layilin, A Novel Talin-binding Transmembrane Protein Homologous with C-type Lectins, is Localized in Membrane Ruffles

Mark L. Borowsky, Richard O. Hynes
Journal: Journal of Cell Biology
J Cell Biol (1998) 143 (2): 429–442.
https://doi.org/10.1083/jcb.143.2.429
Published: 19 October 1998
View article titled, Layilin, A Novel Talin-binding Transmembrane Protein Homologous with C-type Lectins, is Localized in Membrane Ruffles
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Journal Articles

Novel Roles for α3β1 Integrin as a Regulator of Cytoskeletal Assembly and as a Trans-dominant Inhibitor of Integrin Receptor Function in Mouse Keratinocytes

Kairbaan M. Hodivala-Dilke, C. Michael DiPersio, Jordan A. Kreidberg, Richard O. Hynes
Journal: Journal of Cell Biology
J Cell Biol (1998) 142 (5): 1357–1369.
https://doi.org/10.1083/jcb.142.5.1357
Published: 07 September 1998
View article titled, Novel Roles for α3β1 Integrin as a Regulator of Cytoskeletal Assembly and as a Trans-dominant Inhibitor of Integrin Receptor Function in Mouse Keratinocytes
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Journal Articles

Hematopoietic Progenitor Cell Rolling in Bone Marrow Microvessels: Parallel Contributions by Endothelial Selectins and Vascular Cell Adhesion Molecule 1

Irina B. Mazo, Jose-Carlos Gutierrez-Ramos, Paul S. Frenette, Richard O. Hynes, Denisa D. Wagner, Ulrich H. von Andrian
Journal: Journal of Experimental Medicine
J Exp Med (1998) 188 (3): 465–474.
https://doi.org/10.1084/jem.188.3.465
Published: 03 August 1998
View article titled, Hematopoietic Progenitor Cell Rolling in Bone Marrow Microvessels: Parallel Contributions by Endothelial Selectins and Vascular Cell Adhesion Molecule 1
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Journal Articles

Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases

Edwin A. Clark, Warren G. King, Joan S. Brugge, Marc Symons, Richard O. Hynes
Journal: Journal of Cell Biology
J Cell Biol (1998) 142 (2): 573–586.
https://doi.org/10.1083/jcb.142.2.573
Published: 27 July 1998
View article titled, Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases
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Journal Articles

Precocious Mammary Gland Development in P-Cadherin–deficient Mice

Glenn L. Radice, M. Celeste Ferreira-Cornwell, Stephen D. Robinson, Helen Rayburn, Lewis A. Chodosh, Masatoshi Takeichi, Richard O. Hynes
Journal: Journal of Cell Biology
J Cell Biol (1997) 139 (4): 1025–1032.
https://doi.org/10.1083/jcb.139.4.1025
Published: 17 November 1997
View article titled, Precocious Mammary Gland Development in P-Cadherin–deficient Mice
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Journal Articles

Fusion Competence of Myoblasts Rendered Genetically Null for N-Cadherin in Culture

Carol A. Charlton, William A. Mohler, Glenn L. Radice, Richard O. Hynes, Helen M. Blau
Journal: Journal of Cell Biology
J Cell Biol (1997) 138 (2): 331–336.
https://doi.org/10.1083/jcb.138.2.331
Published: 28 July 1997
View article titled, Fusion Competence of Myoblasts Rendered Genetically Null for N-Cadherin in Culture
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Journal Articles

α3β1 Integrin Is Required for Normal Development of the Epidermal Basement Membrane

C. Michael DiPersio, Kairbaan M. Hodivala-Dilke, Rudolf Jaenisch, Jordan A. Kreidberg, Richard O. Hynes
Journal: Journal of Cell Biology
J Cell Biol (1997) 137 (3): 729–742.
https://doi.org/10.1083/jcb.137.3.729
Published: 05 May 1997
View article titled, α3β1 Integrin Is Required for Normal Development of the Epidermal Basement Membrane
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Journal Articles

CHARACTERIZATION OF THE EXTERNAL PROTEINS OF HAMSTER FIBROBLASTS

Richard O. Hynes, Kenneth C. Humphryes
Journal: Journal of Cell Biology
J Cell Biol (1974) 62 (2): 438–448.
https://doi.org/10.1083/jcb.62.2.438
Published: 01 August 1974
View article titled, CHARACTERIZATION OF THE EXTERNAL PROTEINS OF HAMSTER FIBROBLASTS
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