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Johan Auwerx
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Journal Articles

The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression

In Special Collection:
Fibrosis Collection 2023 , Metabolism Signaling
Giorgia Benegiamo, Giacomo V.G. von Alvensleben, Sandra Rodríguez-López, Ludger J.E. Goeminne, Alexis M. Bachmann, Jean-David Morel, Ellen Broeckx, Jing Ying Ma, Vinicius Carreira, Sameh A. Youssef, Nabil Azhar, Dermot F. Reilly, Katharine D’Aquino, Shannon Mullican, Maroun Bou-Sleiman, Johan Auwerx
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (4): e20221738.
https://doi.org/10.1084/jem.20221738
Published: 14 February 2023
View article titled, The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression
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Includes: Supplementary data
Journal Articles

V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans

Terytty Yang Li, Arwen W. Gao, Xiaoxu Li, Hao Li, Yasmine J. Liu, Amelia Lalou, Nagammal Neelagandan, Felix Naef, Kristina Schoonjans, Johan Auwerx
Journal: Journal of Cell Biology
J Cell Biol (2022) 222 (1): e202205045.
https://doi.org/10.1083/jcb.202205045
Published: 31 October 2022
View article titled, V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans
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Includes: Supplementary data
Journal Articles

GCN5 maintains muscle integrity by acetylating YY1 to promote dystrophin expression

Gregory C. Addicks, Hongbo Zhang, Dongryeol Ryu, Goutham Vasam, Alexander E. Green, Philip L. Marshall, Sonia Patel, Baeki E. Kang, Doyoun Kim, Elena Katsyuba, Evan G. Williams, Jean-Marc Renaud, Johan Auwerx, Keir J. Menzies
Journal: Journal of Cell Biology
J Cell Biol (2022) 221 (2): e202104022.
https://doi.org/10.1083/jcb.202104022
Published: 13 January 2022
View article titled, GCN5 maintains muscle integrity by acetylating YY1 to promote dystrophin expression
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Includes: Supplementary data
Journal Articles

Confounding factors from inducible systems for spatiotemporal gene expression regulation

In Special Collection:
Reproducibility and Best Practices in Cell Biology
Rob C.I. Wüst, Riekelt H. Houtkooper, Johan Auwerx
Journal: Journal of Cell Biology
Series: Reproducibility
J Cell Biol (2020) 219 (7): e202003031.
https://doi.org/10.1083/jcb.202003031
Published: 19 May 2020
View article titled, Confounding factors from inducible systems for spatiotemporal gene expression regulation
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Journal Articles

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

In Special Collection:
Cellular Mechanisms of Aging , JCB65: Mitochondria
Pedro M. Quirós, Miguel A. Prado, Nicola Zamboni, Davide D’Amico, Robert W. Williams, Daniel Finley, Steven P. Gygi, Johan Auwerx
Journal: Journal of Cell Biology
J Cell Biol (2017) 216 (7): 2027–2045.
https://doi.org/10.1083/jcb.201702058
Published: 31 May 2017
View article titled, Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals
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Includes: Supplementary data
Journal Articles

Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis

Hyo Kyun Chung, Dongryeol Ryu, Koon Soon Kim, Joon Young Chang, Yong Kyung Kim, Hyon-Seung Yi, Seul Gi Kang, Min Jeong Choi, Seong Eun Lee, Saet-Byel Jung, Min Jeong Ryu, Soung Jung Kim, Gi Ryang Kweon, Hail Kim, Jung Hwan Hwang, Chul-Ho Lee, Se-Jin Lee, Christopher E. Wall, Michael Downes, Ronald M. Evans, Johan Auwerx, Minho Shong
Journal: Journal of Cell Biology
J Cell Biol (2016) 216 (1): 149–165.
https://doi.org/10.1083/jcb.201607110
Published: 16 December 2016
View article titled, Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis
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Includes: Supplementary data
Journal Articles

Exploring the therapeutic space around NAD+

Riekelt H. Houtkooper, Johan Auwerx
Journal: Journal of Cell Biology
J Cell Biol (2012) 199 (2): 205–209.
https://doi.org/10.1083/jcb.201207019
Published: 15 October 2012
View article titled, Exploring the therapeutic space around NAD+
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Journal Articles

Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator–activated receptor-γ

Christel Rousseaux, Bruno Lefebvre, Laurent Dubuquoy, Philippe Lefebvre, Olivier Romano, Johan Auwerx, Daniel Metzger, Walter Wahli, Béatrice Desvergne, Gian Carlo Naccari, Philippe Chavatte, Amaury Farce, Philippe Bulois, Antoine Cortot, Jean Frédéric Colombel, Pierre Desreumaux
Journal: Journal of Experimental Medicine
J Exp Med (2005) 201 (8): 1205–1215.
https://doi.org/10.1084/jem.20041948
Published: 11 April 2005
View article titled, Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator–activated receptor-γ
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Journal Articles

Peroxisome Proliferator–activated Receptors α and γ Down-regulate Allergic Inflammation and Eosinophil Activation

Gaetane Woerly, Kohei Honda, Marc Loyens, Jean-Paul Papin, Johan Auwerx, Bart Staels, Monique Capron, David Dombrowicz
Journal: Journal of Experimental Medicine
J Exp Med (2003) 198 (3): 411–421.
https://doi.org/10.1084/jem.20021384
Published: 04 August 2003
View article titled, Peroxisome Proliferator–activated Receptors α and γ Down-regulate Allergic Inflammation and Eosinophil Activation
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Journal Articles

Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer: A Basis for New Therapeutic Strategies

Pierre Desreumaux, Laurent Dubuquoy, Sophie Nutten, Michel Peuchmaur, Walter Englaro, Kristina Schoonjans, Benoit Derijard, Beatrice Desvergne, Walter Wahli, Pierre Chambon, Mark D. Leibowitz, Jean-Frédéric Colombel, Johan Auwerx
Journal: Journal of Experimental Medicine
J Exp Med (2001) 193 (7): 827–838.
https://doi.org/10.1084/jem.193.7.827
Published: 02 April 2001
View article titled, Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer: A Basis for New Therapeutic Strategies
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