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Journal Articles

Heterozygous human JAK2V617F activates AhR to drive essential thrombocythemia and promote thrombosis

Li Zhou, Dongxiao Wu, Yabo Zhou, Dianheng Wang, Zhuo-Yu An, Peng Zhao, Shaoyang Lai, Zhenfeng Wang, Nannan Zhou, Jie Chen, Jiadi Lv, Xiaohui Zhang, Bo Huang
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (12): e20250153.
https://doi.org/10.1084/jem.20250153
Published: 15 October 2025
View article titled, Heterozygous human JAK2V617F activates AhR to drive essential thrombocythemia and promote thrombosis
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Includes: Supplementary data
Journal Articles

Specific loading of oncolytic VSV on CAR enhances CAR-T cell signaling and antitumor activity

In Special Collection:
JEM Cancer Immunotherapy 2025
Fan Xing, Xuemei Wang, Zeying Li, Liangying Zheng, Zuda Huang, Jieqing Guo, Zhihui Xi, Huolun Feng, Baijin Xia, Yingtong Lin, Fei Yu, Jie Chen, Hui Zhang
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (11): e20241851.
https://doi.org/10.1084/jem.20241851
Published: 12 September 2025
View article titled, Specific loading of oncolytic VSV on CAR enhances CAR-T cell signaling and antitumor activity
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Includes: Supplementary data
Journal Articles

The Cby3/ciBAR1 complex positions the annulus along the sperm flagellum during spermiogenesis

Mohammed Hoque, Feng-Qian Li, William David Weber, Jun Jie Chen, Eunice N. Kim, Pao-Lin Kuo, Pablo E. Visconti, Ken-Ichi Takemaru
Journal: Journal of Cell Biology
J Cell Biol (2024) 223 (3): e202307147.
https://doi.org/10.1083/jcb.202307147
Published: 10 January 2024
View article titled, The Cby3/ciBAR1 complex positions the annulus along the sperm flagellum during spermiogenesis
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Includes: Supplementary data
Journal Articles

Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication

In Special Collection:
Lipid and Membrane Biology 2023
Jeffrey M. Williams, Yu-Jie Chen, Woo Jung Cho, Andrew W. Tai, Billy Tsai
Journal: Journal of Cell Biology
J Cell Biol (2023) 222 (7): e202203060.
https://doi.org/10.1083/jcb.202203060
Published: 24 April 2023
View article titled, Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication
Open the PDF for Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication in another window
Includes: Supplementary data
Journal Articles

A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes

In Special Collection:
JEM Clinical Immunology Collection 2022
Paul Bastard, Kuang-Chih Hsiao, Qian Zhang, Jeremy Choin, Emma Best, Jie Chen, Adrian Gervais, Lucy Bizien, Marie Materna, Christine Harmant, Maguelonne Roux, Nicola L. Hawley, Daniel E. Weeks, Stephen T. McGarvey, Karla Sandoval, Carmina Barberena-Jonas, Consuelo D. Quinto-Cortés, Erika Hagelberg, Alexander J. Mentzer, Kathryn Robson, Boubacar Coulibaly, Yoann Seeleuthner, Benedetta Bigio, Zhi Li, Gilles Uzé, Sandra Pellegrini, Lazaro Lorenzo, Zineb Sbihi, Sylvain Latour, Marianne Besnard, Tiphaine Adam de Beaumais, Evelyne Jacqz Aigrain, Vivien Béziat, Ranjan Deka, Litara Esera Tulifau, Satupa‘itea Viali, Muagututi‘a Sefuiva Reupena, Take Naseri, Peter McNaughton, Vanessa Sarkozy, Jane Peake, Annaliesse Blincoe, Sarah Primhak, Simon Stables, Kate Gibson, See-Tarn Woon, Kylie Marie Drake, Adrian V.S. Hill, Cheng-Yee Chan, Richard King, Rohan Ameratunga, Iotefa Teiti, Maite Aubry, Van-Mai Cao-Lormeau, Stuart G. Tangye, Shen-Ying Zhang, Emmanuelle Jouanguy, Paul Gray, Laurent Abel, Andrés Moreno-Estrada, Ryan L. Minster, Lluis Quintana-Murci, Andrew C. Wood, Jean-Laurent Casanova
Journal: Journal of Experimental Medicine
J Exp Med (2022) 219 (6): e20220028.
https://doi.org/10.1084/jem.20220028
Published: 20 April 2022
View article titled, A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes
Open the PDF for A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes in another window
Includes: Supplementary data
Journal Articles

Inborn errors of TLR3- or MDA5-dependent type I IFN immunity in children with enterovirus rhombencephalitis

In Special Collection:
Innate Immunity: From Basic Biology to Human Disease
Jie Chen, Huie Jing, Andrea Martin-Nalda, Paul Bastard, Jacques G. Rivière, Zhiyong Liu, Roger Colobran, Danyel Lee, Wesley Tung, Jeremy Manry, Mary Hasek, Soraya Boucherit, Lazaro Lorenzo, Flore Rozenberg, Mélodie Aubart, Laurent Abel, Helen C. Su, Pere Soler Palacin, Jean-Laurent Casanova, Shen-Ying Zhang
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (12): e20211349.
https://doi.org/10.1084/jem.20211349
Published: 02 November 2021
View article titled, Inborn errors of TLR3- or MDA5-dependent type I IFN immunity in children with enterovirus rhombencephalitis
Open the PDF for Inborn errors of TLR3- or MDA5-dependent type I IFN immunity in children with enterovirus rhombencephalitis in another window
Includes: Supplementary data
Journal Articles

Reticulon protects the integrity of the ER membrane during ER escape of large macromolecular protein complexes

Yu-Jie Chen, Jeffrey M. Williams, Peter Arvan, Billy Tsai
Journal: Journal of Cell Biology
J Cell Biol (2020) 219 (2): e201908182.
https://doi.org/10.1083/jcb.201908182
Published: 01 January 2020
View article titled, Reticulon protects the integrity of the ER membrane during ER escape of large macromolecular protein complexes
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Includes: Supplementary data
Journal Articles

Severe influenza pneumonitis in children with inherited TLR3 deficiency

Hye Kyung Lim, Sarah X.L. Huang, Jie Chen, Gaspard Kerner, Olivier Gilliaux, Paul Bastard, Kerry Dobbs, Nicholas Hernandez, Nicolas Goudin, Mary L. Hasek, Eduardo Javier García Reino, Fabien G. Lafaille, Lazaro Lorenzo, Priya Luthra, Tatiana Kochetkov, Benedetta Bigio, Soraya Boucherit, Flore Rozenberg, Catherine Vedrinne, Michael D. Keller, Yuval Itan, Adolfo García-Sastre, Marie Celard, Jordan S. Orange, Michael J. Ciancanelli, Isabelle Meyts, Qian Zhang, Laurent Abel, Luigi D. Notarangelo, Hans-Willem Snoeck, Jean-Laurent Casanova, Shen-Ying Zhang
Journal: Journal of Experimental Medicine
J Exp Med (2019) 216 (9): 2038–2056.
https://doi.org/10.1084/jem.20181621
Published: 19 June 2019
View article titled, Severe influenza pneumonitis in children with inherited TLR3 deficiency
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Includes: Supplementary data
Journal Articles

Class III PI-3-kinase activates phospholipase D in an amino acid–sensing mTORC1 pathway

Mee-Sup Yoon, Guangwei Du, Jonathan M. Backer, Michael A. Frohman, Jie Chen
Journal: Journal of Cell Biology
J Cell Biol (2011) 195 (3): 435–447.
https://doi.org/10.1083/jcb.201107033
Published: 24 October 2011
View article titled, Class III PI-3-kinase activates phospholipase D in an amino acid–sensing mTORC1 pathway
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Includes: Supplementary data
Journal Articles

IGF-II is regulated by microRNA-125b in skeletal myogenesis

Yejing Ge, Yuting Sun, Jie Chen
Journal: Journal of Cell Biology
J Cell Biol (2011) 192 (1): 69–81.
https://doi.org/10.1083/jcb.201007165
Published: 03 January 2011
View article titled, IGF-II is regulated by microRNA-125b in skeletal myogenesis
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Includes: Supplementary data
Journal Articles

Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis

Yuting Sun, Yejing Ge, Jenny Drnevich, Yong Zhao, Mark Band, Jie Chen
Journal: Journal of Cell Biology
J Cell Biol (2010) 189 (7): 1157–1169.
https://doi.org/10.1083/jcb.200912093
Published: 21 June 2010
View article titled, Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis
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Includes: Multimedia, Supplementary data
Journal Articles

IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients

Ebru Erbay, In-Hyun Park, Paul D. Nuzzi, Christopher J. Schoenherr, Jie Chen
Journal: Journal of Cell Biology
J Cell Biol (2003) 163 (5): 931–936.
https://doi.org/10.1083/jcb.200307158
Published: 08 December 2003
View article titled, IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients
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