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Journal Articles

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8 + T cells

Luca Gattinoni, Steven E. Finkelstein, Christopher A. Klebanoff, Paul A. Antony, Douglas C. Palmer, Paul J. Spiess, Leroy N. Hwang, Zhiya Yu, Claudia Wrzesinski, David M. Heimann, Charles D. Surh, Steven A. Rosenberg, Nicholas P. Restifo
Journal: Journal of Experimental Medicine
J Exp Med (2005) 202 (7): 907–912.
https://doi.org/10.1084/jem.20050732
Published: 03 October 2005
View article titled, Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8 + T cells
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Includes: Supplementary data
Journal Articles

Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells

Willem W. Overwijk, Marc R. Theoret, Steven E. Finkelstein, Deborah R. Surman, Laurina A. de Jong, Florry A. Vyth-Dreese, Trees A. Dellemijn, Paul A. Antony, Paul J. Spiess, Douglas C. Palmer, David M. Heimann, Christopher A. Klebanoff, Zhiya Yu, Leroy N. Hwang, Lionel Feigenbaum, Ada M. Kruisbeek, Steven A. Rosenberg, Nicholas P. Restifo
Journal: Journal of Experimental Medicine
J Exp Med (2003) 198 (4): 569–580.
https://doi.org/10.1084/jem.20030590
Published: 18 August 2003
View article titled, Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells
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Journal Articles

A nonimmunogenic sarcoma transduced with the cDNA for interferon gamma elicits CD8+ T cells against the wild-type tumor: correlation with antigen presentation capability.

N P Restifo, P J Spiess, S E Karp, J J Mulé, S A Rosenberg
Journal: Journal of Experimental Medicine
J Exp Med (1992) 175 (6): 1423–1431.
https://doi.org/10.1084/jem.175.6.1423
Published: 01 June 1992
View article titled, A nonimmunogenic sarcoma transduced with the cDNA for interferon gamma elicits CD8+ T cells against the wild-type tumor: correlation with antigen presentation capability.
Open the PDF for A nonimmunogenic sarcoma transduced with the cDNA for interferon gamma elicits CD8+ T cells against the wild-type tumor: correlation with antigen presentation capability. in another window
Journal Articles

Interferon gamma and tumor necrosis factor have a role in tumor regressions mediated by murine CD8+ tumor-infiltrating lymphocytes.

R J Barth, Jr, J J Mulé, P J Spiess, S A Rosenberg
Journal: Journal of Experimental Medicine
J Exp Med (1991) 173 (3): 647–658.
https://doi.org/10.1084/jem.173.3.647
Published: 01 March 1991
View article titled, Interferon gamma and tumor necrosis factor have a role in tumor regressions mediated by murine CD8+ tumor-infiltrating lymphocytes.
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Journal Articles

Synergistic antitumor activity of tumor-infiltrating lymphocytes, interleukin 2, and local tumor irradiation. Studies on the mechanism of action.

R B Cameron, P J Spiess, S A Rosenberg
Journal: Journal of Experimental Medicine
J Exp Med (1990) 171 (1): 249–263.
https://doi.org/10.1084/jem.171.1.249
Published: 01 January 1990
View article titled, Synergistic antitumor activity of tumor-infiltrating lymphocytes, interleukin 2, and local tumor irradiation. Studies on the mechanism of action.
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Journal Articles

Cotranslational and posttranslational proteolytic processing of preprosomatostatin-I in intact islet tissue.

B D Noe, P C Andrews, J E Dixon, J Spiess
Journal: Journal of Cell Biology
J Cell Biol (1986) 103 (4): 1205–1211.
https://doi.org/10.1083/jcb.103.4.1205
Published: 01 October 1986
View article titled, Cotranslational and posttranslational proteolytic processing of preprosomatostatin-I in intact islet tissue.
Open the PDF for Cotranslational and posttranslational proteolytic processing of preprosomatostatin-I in intact islet tissue. in another window
Journal Articles

Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2.

S A Rosenberg, J J Mulé, P J Spiess, C M Reichert, S L Schwarz
Journal: Journal of Experimental Medicine
J Exp Med (1985) 161 (5): 1169–1188.
https://doi.org/10.1084/jem.161.5.1169
Published: 01 May 1985
View article titled, Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2.
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Journal Articles

Comparison of prohormone-processing activities in islet microsomes and secretory granules: evidence for distinct converting enzymes for separate islet prosomatostatins.

B D Noe, G Debo, J Spiess
Journal: Journal of Cell Biology
J Cell Biol (1984) 99 (2): 578–587.
https://doi.org/10.1083/jcb.99.2.578
Published: 01 August 1984
View article titled, Comparison of prohormone-processing activities in islet microsomes and secretory granules: evidence for distinct converting enzymes for separate islet prosomatostatins.
Open the PDF for Comparison of prohormone-processing activities in islet microsomes and secretory granules: evidence for distinct converting enzymes for separate islet prosomatostatins. in another window