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Journal Articles

Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production

In Special Collection:
Hematology and Stem Cells 2023
Yoon-A Kang, Hyojung Paik, Si Yi Zhang, Jonathan J. Chen, Oakley C. Olson, Carl A. Mitchell, Amelie Collins, James W. Swann, Matthew R. Warr, Rong Fan, Emmanuelle Passegué
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20230088.
https://doi.org/10.1084/jem.20230088
Published: 26 April 2023
View article titled, Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production
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Includes: Supplementary data
Journal Articles

TBK1 recruitment to STING mediates autoinflammatory arthritis caused by defective DNA clearance

Tong Li, Seoyun Yum, Minghao Li, Xiang Chen, Xiaoxia Zuo, Zhijian J. Chen
Journal: Journal of Experimental Medicine
J Exp Med (2021) 219 (1): e20211539.
https://doi.org/10.1084/jem.20211539
Published: 13 December 2021
View article titled, TBK1 recruitment to STING mediates autoinflammatory arthritis caused by defective DNA clearance
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Journal Articles

Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle

Yuntao Xia, Charlotte R. Pfeifer, Kuangzheng Zhu, Jerome Irianto, Dazhen Liu, Kalia Pannell, Emily J. Chen, Lawrence J. Dooling, Michael P. Tobin, Mai Wang, Irena L. Ivanovska, Lucas R. Smith, Roger A. Greenberg, Dennis E. Discher
Journal: Journal of Cell Biology
J Cell Biol (2019) 218 (8): 2545–2563.
https://doi.org/10.1083/jcb.201811100
Published: 25 June 2019
View article titled, Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle
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Includes: Supplementary data
Journal Articles

The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer

In Special Collection:
Cytokines 2018 , Innate Immune Sensors in Health and Disease , JEM Cancer Collection 2019 , JEM Reviews Collection , Scientific and Technical Advances in Cancer Immunology 2019
Tuo Li, Zhijian J. Chen
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (5): 1287–1299.
https://doi.org/10.1084/jem.20180139
Published: 05 April 2018
View article titled, The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer
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Journal Articles

TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects

Min-Kyung Choo, Yasuyo Sano, Changhoon Kim, Kei Yasuda, Xiao-Dong Li, Xin Lin, Mary Stenzel-Poore, Lena Alexopoulou, Sankar Ghosh, Eicke Latz, Ian R. Rifkin, Zhijian J. Chen, George C. Stewart, Hyonyong Chong, Jin Mo Park
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (5): 1297–1311.
https://doi.org/10.1084/jem.20161141
Published: 11 April 2017
View article titled, TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects
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Journal Articles

Flow-induced protein kinase A–CREB pathway acts via BMP signaling to promote HSC emergence

Peter Geon Kim, Haruko Nakano, Partha P. Das, Michael J. Chen, R. Grant Rowe, Stephanie S. Chou, Samantha J. Ross, Kathleen M. Sakamoto, Leonard I. Zon, Thorsten M. Schlaeger, Stuart H. Orkin, Atsushi Nakano, George Q. Daley
Journal: Journal of Experimental Medicine
J Exp Med (2015) 212 (5): 633–648.
https://doi.org/10.1084/jem.20141514
Published: 13 April 2015
View article titled, Flow-induced protein kinase A–CREB pathway acts via BMP signaling to promote HSC emergence
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Includes: Supplementary data
Journal Articles

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

Lili Jing, Owen J. Tamplin, Michael J. Chen, Qing Deng, Shenia Patterson, Peter G. Kim, Ellen M. Durand, Ashley McNeil, Julie M. Green, Shinobu Matsuura, Julien Ablain, Margot K. Brandt, Thorsten M. Schlaeger, Anna Huttenlocher, George Q. Daley, Katya Ravid, Leonard I. Zon
Journal: Journal of Experimental Medicine
J Exp Med (2015) 212 (5): 649–663.
https://doi.org/10.1084/jem.20141528
Published: 13 April 2015
View article titled, Adenosine signaling promotes hematopoietic stem and progenitor cell emergence
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Includes: Supplementary data
Journal Articles

Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair

Shichuan Zhang, Hirohiko Yajima, HoangDinh Huynh, Junke Zheng, Elsa Callen, Hua-Tang Chen, Nancy Wong, Samuel Bunting, Yu-Fen Lin, Mengxia Li, Kyung-Jone Lee, Michael Story, Eric Gapud, Barry P. Sleckman, André Nussenzweig, Cheng Cheng Zhang, David J. Chen, Benjamin P.C. Chen
Journal: Journal of Cell Biology
J Cell Biol (2011) 193 (2): 295–305.
https://doi.org/10.1083/jcb.201009074
Published: 11 April 2011
View article titled, Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair
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Includes: Supplementary data
Journal Articles

Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

Sarah L. Jongbloed, Andrew J. Kassianos, Kylie J. McDonald, Georgina J. Clark, Xinsheng Ju, Catherine E. Angel, Chun-Jen J. Chen, P. Rod Dunbar, Robert B. Wadley, Varinder Jeet, Annelie J.E. Vulink, Derek N.J. Hart, Kristen J. Radford
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (6): 1247–1260.
https://doi.org/10.1084/jem.20092140
Published: 17 May 2010
View article titled, Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens
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Includes: Supplementary data
Journal Articles

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites

Sairei So, Anthony J. Davis, David J. Chen
Journal: Journal of Cell Biology
J Cell Biol (2010) 188 (3): 443.
https://doi.org/10.1083/jcb.20090606420100113c
Published: 08 February 2010
View article titled, Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites
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Journal Articles

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites

Sairei So, Anthony J. Davis, David J. Chen
Journal: Journal of Cell Biology
J Cell Biol (2009) 187 (7): 977–990.
https://doi.org/10.1083/jcb.200906064
Published: 21 December 2009
View article titled, Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites
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Includes: Supplementary data
Journal Articles

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP

Sarah M. McWhirter, Roman Barbalat, Kathryn M. Monroe, Mary F. Fontana, Mamoru Hyodo, Nathalie T. Joncker, Ken J. Ishii, Shizuo Akira, Marco Colonna, Zhijian J. Chen, Katherine A. Fitzgerald, Yoshihiro Hayakawa, Russell E. Vance
Journal: Journal of Experimental Medicine
J Exp Med (2009) 206 (9): 1899–1911.
https://doi.org/10.1084/jem.20082874
Published: 03 August 2009
View article titled, A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
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Includes: Supplementary data
Journal Articles

DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys?

Eric Weterings, David J. Chen
Journal: Journal of Cell Biology
J Cell Biol (2007) 179 (2): 183–186.
https://doi.org/10.1083/jcb.200705106
Published: 15 October 2007
View article titled, DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys?
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Journal Articles

Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

Naoya Uematsu, Eric Weterings, Ken-ichi Yano, Keiko Morotomi-Yano, Burkhard Jakob, Gisela Taucher-Scholz, Pierre-Olivier Mari, Dik C. van Gent, Benjamin P.C. Chen, David J. Chen
Journal: Journal of Cell Biology
J Cell Biol (2007) 177 (2): 219–229.
https://doi.org/10.1083/jcb.200608077
Published: 16 April 2007
View article titled, Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks
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Includes: Supplementary data
Journal Articles

Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells

Jong-Soo Kim, Tatiana B. Krasieva, Hitoshi Kurumizaka, David J. Chen, A. Malcolm R. Taylor, Kyoko Yokomori
Journal: Journal of Cell Biology
J Cell Biol (2005) 170 (3): 341–347.
https://doi.org/10.1083/jcb.200411083
Published: 01 August 2005
View article titled, Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells
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Includes: Supplementary data
Journal Articles

Correction

Clint L. Makino, R.L. Dodd, J. Chen, M.E. Burns, A. Roca, M.I. Simon, D.A. Baylor
Journal: Journal of General Physiology
J Gen Physiol (2005) 126 (1): 81.
https://doi.org/10.1085/jgp.200308994061405c
Published: 27 June 2005
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Journal Articles

Recoverin Regulates Light-dependent Phosphodiesterase Activity in Retinal Rods

Clint L. Makino, R.L. Dodd, J. Chen, M.E. Burns, A. Roca, M.I. Simon, D.A. Baylor
Journal: Journal of General Physiology
J Gen Physiol (2004) 123 (6): 729–741.
https://doi.org/10.1085/jgp.200308994
Published: 01 June 2004
View article titled, Recoverin Regulates Light-dependent Phosphodiesterase Activity in Retinal Rods
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Journal Articles

LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway

Esther J. Chen, Chris A. Kaiser
Journal: Journal of Cell Biology
J Cell Biol (2003) 161 (2): 333–347.
https://doi.org/10.1083/jcb.200210141
Published: 28 April 2003
View article titled, LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway
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Journal Articles

Ku70 Is Required for DNA Repair but Not for T Cell Antigen Receptor Gene Recombination In Vivo

Honghai Ouyang, Andre Nussenzweig, Akihiro Kurimasa, Vera da Costa Soares, Xiaoling Li, Carlos Cordon-Cardo, Wen-hui Li, Nge Cheong, Michel Nussenzweig, George Iliakis, David J. Chen, Gloria C. Li
Journal: Journal of Experimental Medicine
J Exp Med (1997) 186 (6): 921–929.
https://doi.org/10.1084/jem.186.6.921
Published: 15 September 1997
View article titled, Ku70 Is Required for DNA Repair but Not for T Cell Antigen Receptor Gene Recombination In Vivo
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Journal Articles

Interleukin-10 inhibits tumor metastasis through an NK cell-dependent mechanism.

L M Zheng, D M Ojcius, F Garaud, C Roth, E Maxwell, Z Li, H Rong, J Chen, X Y Wang, J J Catino, I King
Journal: Journal of Experimental Medicine
J Exp Med (1996) 184 (2): 579–584.
https://doi.org/10.1084/jem.184.2.579
Published: 01 August 1996
View article titled, Interleukin-10 inhibits tumor metastasis through an NK cell-dependent mechanism.
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