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Journal Articles

Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity

In Special Collection:

Autoimmunity 2024 , JEM Immunology Collection 2024

J Exp Med (2024) 221 (4): e20221080.

https://doi.org/10.1084/jem.20221080

Published: 28 February 2024

View article titled, Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity

Includes: Supplementary data

Journal Articles

α-Synuclein modulates tau spreading in mouse brains

In Special Collection:

Neurodegenerative Diseases: Biology & Therapeutics , Neurodegenerative Diseases: Emerging Mechanisms and Therapeutic Opportunities

Fares Bassil, Emily S. Meymand, Hannah J. Brown, Hong Xu, Timothy O. Cox, Shankar Pattabhiraman, Chantal M. Maghames, Qihui Wu, Bin Zhang, John Q. Trojanowski, Virginia M.-Y. Lee

J Exp Med (2020) 218 (1): e20192193.

https://doi.org/10.1084/jem.20192193

Published: 22 October 2020

View article titled, α-Synuclein modulates tau spreading in mouse brains

Includes: Supplementary data

Journal Articles

A life in pictures—Marilyn Gist Farquhar

Jennifer L. Stow, Jaakko Saraste, William J. Brown

J Cell Biol (2020) 219 (2): e202001010.

https://doi.org/10.1083/jcb.202001010

Published: 22 January 2020

View article titled, A life in pictures—Marilyn Gist Farquhar

Journal Articles

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin

Xiaolai Zhou, Lirong Sun, Francisco Bastos de Oliveira, Xiaoyang Qi, William J. Brown, Marcus B. Smolka, Ying Sun, Fenghua Hu

J Cell Biol (2015) 210 (6): 991–1002.

https://doi.org/10.1083/jcb.201502029

Published: 14 September 2015

View article titled, Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin

Includes: Supplementary data

Journal Articles

A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking

Ximing Du, Jaspal Kumar, Charles Ferguson, Timothy A. Schulz, Yan Shan Ong, Wanjin Hong, William A. Prinz, Robert G. Parton, Andrew J. Brown, Hongyuan Yang

J Cell Biol (2011) 192 (1): 121–135.

https://doi.org/10.1083/jcb.201004142

Published: 10 January 2011

View article titled, A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking

Includes: Supplementary data

Journal Articles

The phospholipase complex PAFAH Ib regulates the functional organization of the Golgi complex

Marie E. Bechler, Anne M. Doody, Esther Racoosin, Lin Lin, Kelvin H. Lee, William J. Brown

J Cell Biol (2010) 190 (1): 45–53.

https://doi.org/10.1083/jcb.200908105

Published: 12 July 2010

View article titled, The phospholipase complex PAFAH Ib regulates the functional organization of the Golgi complex

Includes: Supplementary data

Journal Articles

Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis

Kevin D. Smith, Michael A. Fu, Eric J. Brown

J Cell Biol (2009) 187 (1): 15–23.

https://doi.org/10.1083/jcb.200905006

Published: 05 October 2009

View article titled, Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis

Includes: Supplementary data

Journal Articles

Lysophosphatidic acid acyltransferase 3 regulates Golgi complex structure and function

John A. Schmidt, William J. Brown

J Cell Biol (2009) 186 (2): 211–218.

https://doi.org/10.1083/jcb.200904147

Published: 27 July 2009

View article titled, Lysophosphatidic acid acyltransferase 3 regulates Golgi complex structure and function

Includes: Supplementary data

Journal Articles

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

Weihua Fei, Guanghou Shui, Bruno Gaeta, Ximing Du, Lars Kuerschner, Peng Li, Andrew J. Brown, Markus R. Wenk, Robert G. Parton, Hongyuan Yang

J Cell Biol (2008) 180 (3): 473–482.

https://doi.org/10.1083/jcb.200711136

Published: 04 February 2008

View article titled, Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

Includes: Supplementary data

Journal Articles

Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis

Jack Hutcheson, John C. Scatizzi, Emily Bickel, Nathaniel J. Brown, Philippe Bouillet, Andreas Strasser, Harris Perlman

J Exp Med (2005) 201 (12): 1949–1960.

https://doi.org/10.1084/jem.20041484

Published: 20 June 2005

View article titled, Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis

Journal Articles

The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gβγ

Elsa-Noah N'Diaye, Eric J. Brown

J Cell Biol (2003) 163 (5): 1157–1165.

https://doi.org/10.1083/jcb.200307155

Published: 08 December 2003

View article titled, The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gβγ

Journal Articles

Mycobacterium marinum Escapes from Phagosomes and Is Propelled by Actin-based Motility

Luisa M. Stamm, J. Hiroshi Morisaki, Lian-Yong Gao, Robert L. Jeng, Kent L. McDonald, Robyn Roth, Sunao Takeshita, John Heuser, Matthew D. Welch, Eric J. Brown

J Exp Med (2003) 198 (9): 1361–1368.

https://doi.org/10.1084/jem.20031072

Published: 03 November 2003

View article titled, Mycobacterium marinum Escapes from Phagosomes and Is Propelled by Actin-based Motility

Journal Articles

Blockade of T Lymphocyte Costimulation with Cytotoxic T Lymphocyte–Associated Antigen 4–Immunoglobulin (Ctla4ig) Reverses the Cellular Pathology of Psoriatic Plaques, Including the Activation of Keratinocytes, Dendritic Cells, and Endothelial Cells

Judith R. Abrams, Susan L. Kelley, Elizabeth Hayes, Toyoko Kikuchi, Michael J. Brown, Sewon Kang, Mark G. Lebwohl, Cynthia A. Guzzo, Brian V. Jegasothy, Peter S. Linsley, James G. Krueger

J Exp Med (2000) 192 (5): 681–694.

https://doi.org/10.1084/jem.192.5.681

Published: 05 September 2000

View article titled, Blockade of T Lymphocyte Costimulation with Cytotoxic T Lymphocyte–Associated Antigen 4–Immunoglobulin (Ctla4ig) Reverses the Cellular Pathology of Psoriatic Plaques, Including the Activation of Keratinocytes, Dendritic Cells, and Endothelial Cells

Journal Articles

Assessment of Caspase Activities in Intact Apoptotic Thymocytes Using Cell-Permeable Fluorogenic Caspase Substrates

Akira Komoriya, Beverly Z. Packard, Martin J. Brown, Ming-Lei Wu, Pierre A. Henkart

J Exp Med (2000) 191 (11): 1819–1828.

https://doi.org/10.1084/jem.191.11.1819

Published: 30 May 2000

View article titled, Assessment of Caspase Activities in Intact Apoptotic Thymocytes Using Cell-Permeable Fluorogenic Caspase Substrates

Journal Articles

The Src Homology 2 Domain of Vav Is Required for Its Compartmentation to the Plasma Membrane and Activation of C-Jun Nh₂-Terminal Kinase 1

Ramachandran Arudchandran, Martin J. Brown, Matthew J. Peirce, James S. Song, Juan Zhang, Reuben P. Siraganian, Ulrich Blank, Juan Rivera

J Exp Med (2000) 191 (1): 47–60.

https://doi.org/10.1084/jem.191.1.47

Published: 03 January 2000

View article titled, The Src Homology 2 Domain of Vav Is Required for Its Compartmentation to the Plasma Membrane and Activation of C-Jun Nh2-Terminal Kinase 1

Journal Articles

Role of Cholesterol in Formation and Function of a Signaling Complex Involving αvβ3, Integrin-Associated Protein (Cd47), and Heterotrimeric G Proteins

Jennifer M. Green, Alexander Zheleznyak, Jun Chung, Frederik P. Lindberg, Marika Sarfati, William A. Frazier, Eric J. Brown

J Cell Biol (1999) 146 (3): 673–682.

https://doi.org/10.1083/jcb.146.3.673

Published: 09 August 1999

View article titled, Role of Cholesterol in Formation and Function of a Signaling Complex Involving αvβ3, Integrin-Associated Protein (Cd47), and Heterotrimeric G Proteins

Journal Articles

A Molecular Mechanism of Integrin Crosstalk: α_vβ₃Suppression of Calcium/Calmodulin-dependent Protein Kinase II Regulates α₅β₁ Function

Scott D. Blystone, Suzanne E. Slater, Matthew P. Williams, Michael T. Crow, Eric J. Brown

J Cell Biol (1999) 145 (4): 889–897.

https://doi.org/10.1083/jcb.145.4.889

Published: 17 May 1999

View article titled, A Molecular Mechanism of Integrin Crosstalk: αvβ3 Suppression of Calcium/Calmodulin-dependent Protein Kinase II Regulates α5β1 Function

Journal Articles

A Role for the αvβ3 Integrin in the Transmigration of Monocytes

Dheepika Weerasinghe, Kevin P. McHugh, Frederick P. Ross, Eric J. Brown, Roland H. Gisler, Beat A. Imhof

J Cell Biol (1998) 142 (2): 595–607.

https://doi.org/10.1083/jcb.142.2.595

Published: 27 July 1998

View article titled, A Role for the αvβ3 Integrin in the Transmigration of Monocytes

Journal Articles

Stabilization and Localization of Xist RNA are Controlled by Separate Mechanisms and are Not Sufficient for X Inactivation

Christine Moulton Clemson, Jennifer C. Chow, Carolyn J. Brown, Jeanne Bentley Lawrence

J Cell Biol (1998) 142 (1): 13–23.

https://doi.org/10.1083/jcb.142.1.13

Published: 13 July 1998

View article titled, Stabilization and Localization of Xist RNA are Controlled by Separate Mechanisms and are Not Sufficient for X Inactivation

Journal Articles

Role for a Glycan Phosphoinositol Anchor in Fcγ Receptor Synergy

Jennifer M. Green, Alan D. Schreiber, Eric J. Brown

J Cell Biol (1997) 139 (5): 1209–1217.

https://doi.org/10.1083/jcb.139.5.1209

Published: 01 December 1997

View article titled, Role for a Glycan Phosphoinositol Anchor in Fcγ Receptor Synergy

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Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity

α-Synuclein modulates tau spreading in mouse brains

A life in pictures—Marilyn Gist Farquhar

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin

A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking

The phospholipase complex PAFAH Ib regulates the functional organization of the Golgi complex

Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis

Lysophosphatidic acid acyltransferase 3 regulates Golgi complex structure and function

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis

The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gβγ

Mycobacterium marinum Escapes from Phagosomes and Is Propelled by Actin-based Motility

Blockade of T Lymphocyte Costimulation with Cytotoxic T Lymphocyte–Associated Antigen 4–Immunoglobulin (Ctla4ig) Reverses the Cellular Pathology of Psoriatic Plaques, Including the Activation of Keratinocytes, Dendritic Cells, and Endothelial Cells

Assessment of Caspase Activities in Intact Apoptotic Thymocytes Using Cell-Permeable Fluorogenic Caspase Substrates

The Src Homology 2 Domain of Vav Is Required for Its Compartmentation to the Plasma Membrane and Activation of C-Jun Nh₂-Terminal Kinase 1

Role of Cholesterol in Formation and Function of a Signaling Complex Involving αvβ3, Integrin-Associated Protein (Cd47), and Heterotrimeric G Proteins

A Molecular Mechanism of Integrin Crosstalk: α_vβ₃Suppression of Calcium/Calmodulin-dependent Protein Kinase II Regulates α₅β₁ Function

A Role for the αvβ3 Integrin in the Transmigration of Monocytes

Stabilization and Localization of Xist RNA are Controlled by Separate Mechanisms and are Not Sufficient for X Inactivation

Role for a Glycan Phosphoinositol Anchor in Fcγ Receptor Synergy

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