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Heather P. Harding
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Journal Articles

Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis

Markus Tschurtschenthaler, Timon E. Adolph, Jonathan W. Ashcroft, Lukas Niederreiter, Richa Bharti, Svetlana Saveljeva, Joya Bhattacharyya, Magdalena B. Flak, David Q. Shih, Gwenny M. Fuhler, Miles Parkes, Kenji Kohno, Takao Iwawaki, C. Janneke van der Woude, Heather P. Harding, Andrew M. Smith, Maikel P. Peppelenbosch, Stephan R. Targan, David Ron, Philip Rosenstiel, Richard S. Blumberg, Arthur Kaser
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (2): 401–422.
https://doi.org/10.1084/jem.20160791
Published: 12 January 2017
View article titled, Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis
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Includes: Supplementary data
Journal Articles

Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox

Edward Avezov, Benedict C.S. Cross, Gabriele S. Kaminski Schierle, Mikael Winters, Heather P. Harding, Eduardo Pinho Melo, Clemens F. Kaminski, David Ron
Journal: Journal of Cell Biology
J Cell Biol (2013) 201 (2): 337–349.
https://doi.org/10.1083/jcb.201211155
Published: 15 April 2013
View article titled, Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox
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Includes: Supplementary data
Journal Articles

ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

Ester Zito, King-Tung Chin, Jaime Blais, Heather P. Harding, David Ron
Journal: Journal of Cell Biology
J Cell Biol (2010) 189 (4): 769.
https://doi.org/10.1083/jcb.20091108620100423c
Published: 17 May 2010
View article titled, ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis
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Journal Articles

ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

Ester Zito, King-Tung Chin, Jaime Blais, Heather P. Harding, David Ron
Journal: Journal of Cell Biology
J Cell Biol (2010) 188 (6): 821–832.
https://doi.org/10.1083/jcb.200911086
Published: 22 March 2010
View article titled, ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis
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Includes: Supplementary data
Journal Articles

Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux

Jie Shang, Ningguo Gao, Randal J. Kaufman, David Ron, Heather P. Harding, Mark A. Lehrman
Journal: Journal of Cell Biology
J Cell Biol (2007) 176 (5): 605–616.
https://doi.org/10.1083/jcb.200607007
Published: 26 February 2007
View article titled, Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux
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Includes: Supplementary data
Journal Articles

Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK

Stefan J. Marciniak, Lidia Garcia-Bonilla, Junjie Hu, Heather P. Harding, David Ron
Journal: Journal of Cell Biology
J Cell Biol (2006) 172 (2): 201–209.
https://doi.org/10.1083/jcb.200508099
Published: 17 January 2006
View article titled, Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK
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Includes: Supplementary data
Journal Articles

Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ

Wensheng Lin, Heather P. Harding, David Ron, Brian Popko
Journal: Journal of Cell Biology
J Cell Biol (2005) 169 (4): 603–612.
https://doi.org/10.1083/jcb.200502086
Published: 23 May 2005
View article titled, Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ
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Journal Articles

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

In Special Collection:
JCB65: RNA
Phoebe D. Lu, Heather P. Harding, David Ron
Journal: Journal of Cell Biology
J Cell Biol (2004) 167 (1): 27–33.
https://doi.org/10.1083/jcb.200408003
Published: 11 October 2004
View article titled, Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response
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Includes: Supplementary data
Journal Articles

Inhibition of a constitutive translation initiation factor 2α phosphatase, CReP, promotes survival of stressed cells

Céline Jousse, Seiichi Oyadomari, Isabel Novoa, Phoebe Lu, Yuhong Zhang, Heather P. Harding, David Ron
Journal: Journal of Cell Biology
J Cell Biol (2003) 163 (4): 767–775.
https://doi.org/10.1083/jcb.200308075
Published: 24 November 2003
View article titled, Inhibition of a constitutive translation initiation factor 2α phosphatase, CReP, promotes survival of stressed cells
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Journal Articles

Transmission of cell stress from endoplasmic reticulum to mitochondria : enhanced expression of Lon protease

Osamu Hori, Fusae Ichinoda, Takashi Tamatani, Atsushi Yamaguchi, Naoya Sato, Kentaro Ozawa, Yasuko Kitao, Mayuki Miyazaki, Heather P. Harding, David Ron, Masaya Tohyama, David M Stern, Satoshi Ogawa
Journal: Journal of Cell Biology
J Cell Biol (2002) 157 (7): 1151–1160.
https://doi.org/10.1083/jcb.200108103
Published: 24 June 2002
View article titled, Transmission of cell stress from endoplasmic reticulum to mitochondria : enhanced expression of Lon protease
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Journal Articles

Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

Isabel Novoa, Huiqing Zeng, Heather P. Harding, David Ron
Journal: Journal of Cell Biology
J Cell Biol (2001) 153 (5): 1011–1022.
https://doi.org/10.1083/jcb.153.5.1011
Published: 21 May 2001
View article titled, Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α
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