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Journal Articles

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

Florian Klein, Lilian Nogueira, Yoshiaki Nishimura, Ganesh Phad, Anthony P. West, Jr., Ariel Halper-Stromberg, Joshua A. Horwitz, Anna Gazumyan, Cassie Liu, Thomas R. Eisenreich, Clara Lehmann, Gerd Fätkenheuer, Constance Williams, Masashi Shingai, Malcolm A. Martin, Pamela J. Bjorkman, Michael S. Seaman, Susan Zolla-Pazner, Gunilla B. Karlsson Hedestam, Michel C. Nussenzweig
Journal: Journal of Experimental Medicine
J Exp Med (2014) 211 (12): 2361–2372.
https://doi.org/10.1084/jem.20141050
Published: 10 November 2014
View article titled, Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants
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Journal Articles

Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

Ron Diskin, Florian Klein, Joshua A. Horwitz, Ariel Halper-Stromberg, D. Noah Sather, Paola M. Marcovecchio, Terri Lee, Anthony P. West, Jr., Han Gao, Michael S. Seaman, Leonidas Stamatatos, Michel C. Nussenzweig, Pamela J. Bjorkman
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (6): 1235–1249.
https://doi.org/10.1084/jem.20130221
Published: 27 May 2013
View article titled, Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies
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Includes: Supplementary data
Journal Articles

An Inhibitor of Exported Mycobacterium tuberculosis Glutamine Synthetase Selectively Blocks the Growth of Pathogenic Mycobacteria in Axenic Culture and in Human Monocytes: Extracellular Proteins as Potential Novel Drug Targets

Günter Harth, Marcus A. Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1999) 189 (9): 1425–1436.
https://doi.org/10.1084/jem.189.9.1425
Published: 03 May 1999
View article titled, An Inhibitor of Exported Mycobacterium tuberculosis Glutamine Synthetase Selectively Blocks the Growth of Pathogenic Mycobacteria in Axenic Culture and in Human Monocytes: Extracellular Proteins as Potential Novel Drug Targets
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Journal Articles

The Mycobacterium tuberculosis phagosome interacts with early endosomes and is accessible to exogenously administered transferrin.

D L Clemens, M A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1996) 184 (4): 1349–1355.
https://doi.org/10.1084/jem.184.4.1349
Published: 01 October 1996
View article titled, The Mycobacterium tuberculosis phagosome interacts with early endosomes and is accessible to exogenously administered transferrin.
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Journal Articles

Exochelins of Mycobacterium tuberculosis remove iron from human iron-binding proteins and donate iron to mycobactins in the M. tuberculosis cell wall.

J Gobin, M A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1996) 183 (4): 1527–1532.
https://doi.org/10.1084/jem.183.4.1527
Published: 01 April 1996
View article titled, Exochelins of Mycobacterium tuberculosis remove iron from human iron-binding proteins and donate iron to mycobactins in the M. tuberculosis cell wall.
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Journal Articles

Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited.

D L Clemens, M A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1995) 181 (1): 257–270.
https://doi.org/10.1084/jem.181.1.257
Published: 01 January 1995
View article titled, Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited.
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Journal Articles

The role of transforming growth factor beta in the generation of suppression: an interaction between CD8+ T and NK cells.

J D Gray, M Hirokawa, D A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1994) 180 (5): 1937–1942.
https://doi.org/10.1084/jem.180.5.1937
Published: 01 November 1994
View article titled, The role of transforming growth factor beta in the generation of suppression: an interaction between CD8+ T and NK cells.
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Journal Articles

Membrane sorting during phagocytosis: selective exclusion of major histocompatibility complex molecules but not complement receptor CR3 during conventional and coiling phagocytosis.

D L Clemens, M A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1992) 175 (5): 1317–1326.
https://doi.org/10.1084/jem.175.5.1317
Published: 01 May 1992
View article titled, Membrane sorting during phagocytosis: selective exclusion of major histocompatibility complex molecules but not complement receptor CR3 during conventional and coiling phagocytosis.
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Journal Articles

Phenolic glycolipid-1 of Mycobacterium leprae binds complement component C3 in serum and mediates phagocytosis by human monocytes.

L S Schlesinger, M A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1991) 174 (5): 1031–1038.
https://doi.org/10.1084/jem.174.5.1031
Published: 01 November 1991
View article titled, Phenolic glycolipid-1 of Mycobacterium leprae binds complement component C3 in serum and mediates phagocytosis by human monocytes.
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Journal Articles

Complement component C3 fixes selectively to the major outer membrane protein (MOMP) of Legionella pneumophila and mediates phagocytosis of liposome-MOMP complexes by human monocytes.

C Bellinger-Kawahara, M A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1990) 172 (4): 1201–1210.
https://doi.org/10.1084/jem.172.4.1201
Published: 01 October 1990
View article titled, Complement component C3 fixes selectively to the major outer membrane protein (MOMP) of Legionella pneumophila and mediates phagocytosis of liposome-MOMP complexes by human monocytes.
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Journal Articles

Expression and function of chicken integrin beta 1 subunit and its cytoplasmic domain mutants in mouse NIH 3T3 cells.

Y Hayashi, B Haimovich, A Reszka, D Boettiger, A Horwitz
Journal: Journal of Cell Biology
J Cell Biol (1990) 110 (1): 175–184.
https://doi.org/10.1083/jcb.110.1.175
Published: 01 January 1990
View article titled, Expression and function of chicken integrin beta 1 subunit and its cytoplasmic domain mutants in mouse NIH 3T3 cells.
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Journal Articles

Vaccination with the major secretory protein of Legionella pneumophila induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease.

S J Blander, M A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1989) 169 (3): 691–705.
https://doi.org/10.1084/jem.169.3.691
Published: 01 March 1989
View article titled, Vaccination with the major secretory protein of Legionella pneumophila induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease.
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Journal Articles

Phagocytosis of Legionella pneumophila is mediated by human monocyte complement receptors.

N R Payne, M A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1987) 166 (5): 1377–1389.
https://doi.org/10.1084/jem.166.5.1377
Published: 01 November 1987
View article titled, Phagocytosis of Legionella pneumophila is mediated by human monocyte complement receptors.
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Journal Articles

Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes.

M A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1987) 166 (5): 1310–1328.
https://doi.org/10.1084/jem.166.5.1310
Published: 01 November 1987
View article titled, Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes.
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Journal Articles

Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens.

R F Breiman, M A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1987) 165 (3): 799–811.
https://doi.org/10.1084/jem.165.3.799
Published: 01 March 1987
View article titled, Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens.
Open the PDF for Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. in another window
Journal Articles

The cell substrate attachment (CSAT) antigen has properties of a receptor for laminin and fibronectin.

A Horwitz, K Duggan, R Greggs, C Decker, C Buck
Journal: Journal of Cell Biology
J Cell Biol (1985) 101 (6): 2134–2144.
https://doi.org/10.1083/jcb.101.6.2134
Published: 01 December 1985
View article titled, The cell substrate attachment (CSAT) antigen has properties of a receptor for laminin and fibronectin.
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Journal Articles

Isolation and characterization of the cytoplasmic and outer membranes of the Legionnaires' disease bacterium (Legionella pneumophila).

J E Gabay, M A Horwitz
Journal: Journal of Experimental Medicine
J Exp Med (1985) 161 (2): 409–422.
https://doi.org/10.1084/jem.161.2.409
Published: 01 February 1985
View article titled, Isolation and characterization of the cytoplasmic and outer membranes of the Legionnaires' disease bacterium (Legionella pneumophila).
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Journal Articles

Legionella pneumophila inhibits acidification of its phagosome in human monocytes.

M A Horwitz, F R Maxfield
Journal: Journal of Cell Biology
J Cell Biol (1984) 99 (6): 1936–1943.
https://doi.org/10.1083/jcb.99.6.1936
Published: 01 December 1984
View article titled, Legionella pneumophila inhibits acidification of its phagosome in human monocytes.
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Journal Articles

Separation of precursor myogenic and chondrogenic cells in early limb bud mesenchyme by a monoclonal antibody.

J Sasse, A Horwitz, M Pacifici, H Holtzer
Journal: Journal of Cell Biology
J Cell Biol (1984) 99 (5): 1856–1866.
https://doi.org/10.1083/jcb.99.5.1856
Published: 01 November 1984
View article titled, Separation of precursor myogenic and chondrogenic cells in early limb bud mesenchyme by a monoclonal antibody.
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Journal Articles

Adhesive multiplicity in the interaction of embryonic fibroblasts and myoblasts with extracellular matrices.

C Decker, R Greggs, K Duggan, J Stubbs, A Horwitz
Journal: Journal of Cell Biology
J Cell Biol (1984) 99 (4): 1398–1404.
https://doi.org/10.1083/jcb.99.4.1398
Published: 01 October 1984
View article titled, Adhesive multiplicity in the interaction of embryonic fibroblasts and myoblasts with extracellular matrices.
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