The adhesion machinery and interactions with the cellular microenvironment play essential roles in regulating cell function—including proliferation, migration, differentiation—in development and disease. A better understanding of cell–cell and cell–matrix interfaces is crucial to tease apart the mechanisms of developmental and collective migration, mechanotransduction, and cancer cell invasion. In this special collection, JCB Editorial Board member Johanna Ivaska and Senior Scientific Editor Melina Casadio selected recent JCB content delving into the mechanisms of migration, cell–cell, and cell–matrix adhesions. This broad selection includes the works most viewed by our readers and articles chosen for their particular relevance to this collection. We hope you will enjoy these articles and look forward to your comments on social media (@JCellBiol on Twitter).
Image © 2018 Wang et al.