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Structure, Function, and Pharmacology of Ion Channels
This collection provides fundamental insights into the structure, function and pharmacology of a number of different ligand- and voltage-gated ion channels, which will ultimately support the development of new and specific drugs to target monogenic, multigenic, and acquired disease.
Ion channels are transmembrane proteins that are critical components of both excitable and non-excitable cells. Without ion channels, neurons would not be able to communicate with other cells, muscle would not be able to contract and our immune system would not be able to fight infection. Indeed, when ion channels go awry, disease often follows.
Image © 2019 Fryatt et al.

Article
Danna Morales; Tamara Hermosilla; Diego Varela
10.1085/jgp.201812236
Article
Kazuharu Furutani; Kunichika Tsumoto; I-Shan Chen; Kenichiro Handa; Yuko Yamakawa; Jon T. Sack; Yoshihisa Kurachi
10.1085/jgp.201812192
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Alistair G. Fryatt; Sudad Dayl; Anastasios Stavrou; Ralf Schmid; Richard J. Evans
10.1085/jgp.201812108
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Edward Y. Shi; Christine L. Yuan; Matthew T. Sipple; Jayasri Srinivasan; Christopher P. Ptak; Robert E. Oswald; Linda M. Nowak
10.1085/jgp.201812209
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Rocio K. Finol-Urdaneta; Jeffrey R. McArthur; Marcel P. Goldschen-Ohm; Rachelle Gaudet; Denis B. Tikhonov; Boris S. Zhorov; Robert J. French
10.1085/jgp.201812278
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Vinay Idikuda; Weihua Gao; Zhuocheng Su; Qinglian Liu; Lei Zhou
10.1085/jgp.201812019
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Yu Patrick Shi; Samrat Thouta; Yen May Cheng; Tom W. Claydon
10.1085/jgp.201812137
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Timothy J. Wilding; James E. Huettner
10.1085/jgp.201812234
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Sara J. Codding; Matthew C. Trudeau
10.1085/jgp.201812129
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Drew C. Tilley; Juan M. Angueyra; Kenneth S. Eum; Heesoo Kim; Luke H. Chao; Anthony W. Peng; Jon T. Sack
10.1085/jgp.201812213