Figure S4.
A horizontal dot plot representing the normalized expression of canonical gene markers across different cell types. The horizontal axis lists gene markers such as CD19, CD79A, CD3D, GNLY, CD14, and FCGR3B. The vertical axis categorizes cell types into B cells, T cells, NK cells/cytotoxic T cells, Monocytes, and Neutrophils. Each dot represents the mean expression level (Z-score) of a gene marker within a cell type, with the size of the dot indicating the percent of values greater than zero. Redder colors signify higher expression levels. Notable patterns include high expression levels of CD19, CD79A, and MS4A1 in B cells, and significant expression of CD3D, CD3E, and CD3G in T cells. NK cells/cytotoxic T cells show high expression of GNLY, GZMB, and PRF1. Monocytes exhibit high levels of CD14 and CD68, while Neutrophils show notable expression of FCGR3B and ALPL.
Normalized expression of canonical gene markers demonstrated in bubble map plots according to the annotated cell type.