Figure S1.
Two scatter plots showing relative luciferase activity with different plasma proportions. Panel A shows the effect on IFN-alpha 2 activation, with the x-axis labeled Plasma (healthy control) and the y-axis labeled Relative Luciferase activity. The data points are color-coded, with red and pink dots representing different conditions. The plot indicates that a 2% plasma concentration is optimal for assessing IFN-α2 neutralization. Panel B shows the effect on IFN-omega activation, with the same axis labels. Here, plasma concentrations ranging from 0.5% to 2% are suitable for assessing IFN-ω neutralization.

Effects of different proportions of plasma (collected by EDTA-anticoagulated tubes) on IFN-I activation. (A and B) Effects of different proportions of plasma (collected by EDTA-anticoagulated tubes from healthy adults without NAbs) on IFN-α2 (A) and IFN-ω (B) activation.

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