Figure 5.
The horizontal axis represents days before CVID diagnosis, ranging from minus 3500 to 0. The vertical axis lists the patients from 1 to 5. Black lines indicate single-encounter episodes, while amber bars represent extended episodes. A teal dashed line marks the CVID diagnosis date. Each patient's risk score is shown on the right, with teal text indicating correct identification as high-risk and orange text indicating a missed case. Patients 1 to 4 were correctly identified, while patient 5 was missed.
Pre-diagnosis classification in a held-out CVID cohort. Timeline of sinusitis episodes for five CVID patients using only pre-diagnosis data. Encounter states (S1–S6) labeled above each visit. Black lines indicate single-encounter episodes; amber bars represent extended episodes. Teal dashed line marks CVID diagnosis date. Risk scores from the pooled CVID/RTX PheCodes + windowed model are shown for each patient; teal score text indicates correct identification as high-risk; orange score text indicates a missed case. Patients 1–4 were correctly identified; the fifth was missed (80% sensitivity).