The top graph represents Structure 1 at t equals 0.555 microseconds, and the bottom graph represents Structure 2 at t equals 0.775 microseconds. Both graphs plot current in picoamperes on the y-axis and applied potential in millivolts on the x-axis, ranging from minus 250 millivolts to 250 millivolts. The graphs include data points and lines representing different conditions: experimental, positive potentials, and negative potentials. In the top graph, the experimental data are shown in gray, positive potentials in blue, and negative potentials in red. The bottom graph follows the same color scheme. The legends indicate the conductance values for each condition. The data points show a linear relationship between current and applied potential, with slight variations between the conditions. The trends suggest that the conductance changes depending on the applied potential and the structure of ELIC5.
Computational electrophysiology of ELIC5 MD refined structures. The I–V relationships for the ELIC5 MD refined structures (structure 1, top; structure 2, bottom) are shown with the same coloring scheme as Fig. 2 B.
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