Figure S5.
The scatter plot represents the relationship between different treatments and the flaB copy per milligram of tissue in various organs of mice. The horizontal axis represents different organs: Heart base, Urinary Bladder, Quad, and Lymph node. The vertical axis represents the flaB copy per milligram of tissue, with values ranging from 0 to 4 times 10 to the power of 4. The data points are categorized into three groups: Bb plus Hygromycin A, Bb plus Ceftriaxone, and Bb plus PBS, each represented by different symbols: circles, squares, and triangles, respectively. The scatter plot shows that the Bb plus Hygromycin A and Bb plus PBS groups have higher flaB copy numbers in the Heart base and Lymph node compared to the Bb plus Ceftriaxone group, which shows minimal flaB copy numbers across all organs. There are noticeable clusters of higher flaB copy numbers in the Heart base and Lymph node for the Bb plus Hygromycin A and Bb plus PBS groups, indicating similar levels of Bb DNA in these tissues. In contrast, the Bb plus Ceftriaxone group shows no detectable Bb in any of the analyzed tissues.
Analyses of Bb tissue burden following antibiotic treatment. Bb copy numbers (n = 3–5/group) in indicated tissues at 210 dpi from mice receiving a course of treatment with ceftriaxone or hygromycin A, or who were sham-treated. All treatments were initiated at 45 dpi; Quad, right quadriceps. Data represent results from one study of two conducted that gave similar results.